ID A0A0R1UAS3_9LACO Unreviewed; 426 AA.
AC A0A0R1UAS3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=DNA-directed DNA polymerase {ECO:0000313|EMBL:KRL90471.1};
GN ORFNames=FC46_GL001916 {ECO:0000313|EMBL:KRL90471.1};
OS Lactobacillus kalixensis DSM 16043.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423763 {ECO:0000313|EMBL:KRL90471.1, ECO:0000313|Proteomes:UP000051036};
RN [1] {ECO:0000313|EMBL:KRL90471.1, ECO:0000313|Proteomes:UP000051036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16043 {ECO:0000313|EMBL:KRL90471.1,
RC ECO:0000313|Proteomes:UP000051036};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL90471.1}.
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DR EMBL; AZFM01000009; KRL90471.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1UAS3; -.
DR STRING; 1423763.FC46_GL001916; -.
DR PATRIC; fig|1423763.3.peg.1959; -.
DR Proteomes; UP000051036; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProt.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF35; DNA REPAIR PROTEIN HOMOLOG YOBH; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932,
KW ECO:0000313|EMBL:KRL90471.1};
KW Mutator protein {ECO:0000256|ARBA:ARBA00022457};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932,
KW ECO:0000313|EMBL:KRL90471.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022932, ECO:0000313|EMBL:KRL90471.1}.
FT DOMAIN 1..195
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 426 AA; 48806 MW; 41838E8388CBC1F7 CRC64;
MIDNKSFFAS CEALRLGLNP MKAALAVVSQ QPNSDWGSGL IMAASPLAKK KYGLKNVMRA
RDLPDLRKAP DLKIVEPHMN LYIKRSMQIL NIFKKYAADE DIHVYSIDES MIDMTKSWHL
FGDDPYYVGR RIQEDIRNTL GFYTTCGIGE NPLLAKLAMD ISAKHRTSMI DYWHYIDVPD
TIWKISKLED VWGINTRTAE HLRRIGINNM YELAHTDPDI LKKEFGVIGE QLFAMSWGVD
RSIISHKYFP QNKSYGNSQV LTRDYLDQRQ IEIVIREIGE QVAARIRAYG LKVGRIGLFV
GYSFKERENG DRRGGFRIQQ KITPTSNNDE LVRELHALFR KKWHGEAVRT IGVDYSQLNP
DLDQQLSFFM TPEQEIKKRN FDMTVDKIRK KYGFASLVKA SSLLEGATAI RRSILVGGHN
GGNAYE
//
