ID A0A0R1UZH6_9LACO Unreviewed; 875 AA.
AC A0A0R1UZH6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Nuclease SbcCD subunit C {ECO:0000256|ARBA:ARBA00013368};
GN ORFNames=FC21_GL001221 {ECO:0000313|EMBL:KRL96472.1};
OS Limosilactobacillus equigenerosi DSM 18793 = JCM 14505.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=1423742 {ECO:0000313|EMBL:KRL96472.1, ECO:0000313|Proteomes:UP000051084};
RN [1] {ECO:0000313|EMBL:KRL96472.1, ECO:0000313|Proteomes:UP000051084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18793 {ECO:0000313|EMBL:KRL96472.1,
RC ECO:0000313|Proteomes:UP000051084};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBUNIT: Heterodimer of SbcC and SbcD. {ECO:0000256|ARBA:ARBA00011322}.
CC -!- SIMILARITY: Belongs to the SMC family. SbcC subfamily.
CC {ECO:0000256|ARBA:ARBA00006930}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL96472.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZGC01000005; KRL96472.1; -; Genomic_DNA.
DR RefSeq; WP_056995211.1; NZ_AZGC01000005.1.
DR AlphaFoldDB; A0A0R1UZH6; -.
DR STRING; 417373.GCA_001570685_00026; -.
DR PATRIC; fig|1423742.4.peg.1267; -.
DR OrthoDB; 9795626at2; -.
DR Proteomes; UP000051084; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR32114; ABC TRANSPORTER ABCH.3; 1.
DR PANTHER; PTHR32114:SF2; ABC TRANSPORTER ABCH.3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:KRL96472.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:KRL96472.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:KRL96472.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051084}.
FT DOMAIN 5..213
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 180..211
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 313..354
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 463..508
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 540..581
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 875 AA; 99158 MW; F3D9A04233F4B0CC CRC64;
MRPLKLTLDY FGPYEHETVD FTQFNETPLF LITGTTGSGK TTLFDAMCYA LFGKTSNDQR
DARLLRSDFA PDAEDTWVSF WFEHQGVEYQ VKRRVPRLIP GQKSERPTKV SLIYPLQAPE
PTEITKVGEV NQTIEQLLHL QVDQFRQIIL LPQGKFREFL ASSSKDKTEI LRTLFGTQLY
QRWADRLNQD LKQLEQQQTE ATTKMLTLRR QLAVVDDEQP LTAWQTAVAA RITAMQAEQT
QRQAKLQTIQ ALVTKWTQQV QAWEKWQQHH EQLEKISQEI KALRLQEPAM KAQQTTIKLL
EWVQQQSSLL TQVQQLTQQI TKWETQLRTA KQAAKQSQAE LAKLQAKLAT YDDLEQTQRQ
VTLQQAQAAK LAPRWEQLQQ VQTKQTQLER QVAQSQQSLT TATTALAQAE ASWRQLDDQY
VRGQIAQLAQ RLAPDSPCPV CGSCDHPHPA VTTAGETISE SELKQAQATR DQAKMTQAQA
QATLTTQHQQ LQEQQRQQEQ LTAFLQQELA TQSDVAEAYQ AFVAKVASDQ TKLQQRQAEA
EQVKTAVQQA TQILTQAQTQ QQTLQEQLTQ AQAELGTQQA TLQQRIASEQ PTLTLPELME
RATEVVKLPA LRQQVQTFQT KLTAATERYD LLTEQTVIKP SEDQEYVQQA LMQAQAQQQE
LYTAVGKVDE VIEHWQSIRN QVAELAQTYA QTDQQHRQLY DLVTVMRGKG TTKLSFERFV
LQQFFGEVLQ VASQRLLQLT DGRYYFELDQ SLGGVESKVG LEVNVFDEHA GKLRSVHTLS
GGESFMASLS LALALGEVVQ QREGSVKIEA LFVDEGFGSL DQTALEQALA SLQAINGQRM
VGIISHVSEL KAQIPDQLVV TAQHGRSTIS YRHQS
//
