ID A0A0R1WYA5_9LACO Unreviewed; 594 AA.
AC A0A0R1WYA5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Oligoendopeptidase F2 {ECO:0000313|EMBL:KRM19795.1};
GN ORFNames=FC40_GL001314 {ECO:0000313|EMBL:KRM19795.1};
OS Ligilactobacillus hayakitensis DSM 18933 = JCM 14209.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1423755 {ECO:0000313|EMBL:KRM19795.1, ECO:0000313|Proteomes:UP000051054};
RN [1] {ECO:0000313|EMBL:KRM19795.1, ECO:0000313|Proteomes:UP000051054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18933 {ECO:0000313|EMBL:KRM19795.1,
RC ECO:0000313|Proteomes:UP000051054};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU003435};
CC Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC -!- SIMILARITY: Belongs to the peptidase M3 family.
CC {ECO:0000256|RuleBase:RU003435}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM19795.1}.
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DR EMBL; AZGD01000031; KRM19795.1; -; Genomic_DNA.
DR RefSeq; WP_035520296.1; NZ_BAML01000049.1.
DR AlphaFoldDB; A0A0R1WYA5; -.
DR PATRIC; fig|1423755.3.peg.1393; -.
DR eggNOG; COG1164; Bacteria.
DR OrthoDB; 9769691at2; -.
DR Proteomes; UP000051054; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09607; M3B_PepF; 1.
DR Gene3D; 1.10.1370.20; Oligoendopeptidase f, C-terminal domain; 1.
DR Gene3D; 1.20.140.70; Oligopeptidase f, N-terminal domain; 1.
DR InterPro; IPR034006; M3B_PepF_2.
DR InterPro; IPR013647; OligopepF_N_dom.
DR InterPro; IPR042088; OligoPept_F_C.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR InterPro; IPR011977; Pept_M3B_clade3.
DR InterPro; IPR001333; Peptidase_M32_Taq.
DR NCBIfam; TIGR02290; M3_fam_3; 1.
DR PANTHER; PTHR34217:SF1; CARBOXYPEPTIDASE 1; 1.
DR PANTHER; PTHR34217; METAL-DEPENDENT CARBOXYPEPTIDASE; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR Pfam; PF08439; Peptidase_M3_N; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|RuleBase:RU003435};
KW Metal-binding {ECO:0000256|RuleBase:RU003435};
KW Metalloprotease {ECO:0000256|RuleBase:RU003435};
KW Protease {ECO:0000256|RuleBase:RU003435};
KW Reference proteome {ECO:0000313|Proteomes:UP000051054};
KW Zinc {ECO:0000256|RuleBase:RU003435}.
FT DOMAIN 110..176
FT /note="Oligopeptidase F N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08439"
FT DOMAIN 192..574
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
FT COILED 20..54
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 594 AA; 67542 MW; 02D158538E4A35C5 CRC64;
MKEYSEVWDL ESIFAGGSNS AAFQERLEKL KVEIKELEEK ISTWQADAAG LKEILAVMTK
VDEGLSQLGA FAEALSSADV TDSQALQLDS QVMALIPEYS QVNKEFQRSL AQIPDEKWES
LLEDSDLKSV AFVLGEFRRD GANFLSAAEE NIIAQLKLDG QTAWSRHYDV LSGNLKVEHD
NKQLSAGQAF NLMMASKDNE VRDQLFEKWE EAWGKDEQLY ADTLNHIDGA RLTDQKLHGN
TDYLKEPREY NRLKQETLDQ MWAVVAKNKQ SFVEYMNRKA QLLGRQKPVW QDQEAPVVLG
DFEAKHYTFS QAAEFIMENF EKFSPKMAAL AKKAFEGQWI EAQDRPNKRA GGYCTGFPEN
QESRIFMTFG GSVNEVATLA HELGHAFHSS VMWDLPHLNQ GYAMNVAETA STFAEQVVND
AAIASVTSKE EKINLLDQKL QGALAMFFNI HARYIFERSF YEARQTKVLS PKEISDLMVK
AQKEAFADSL ANWHPHFWAA KLHFYIDDVP FYNFPYTFGY LFSQGIYAQA KKVGGSFEDQ
YIALLRDTGA MTTEELAQKH LGVDLTKADF WQAGIDTILE DVKEFMELTE EYVK
//
