ID A0A0R2AGD3_9LACO Unreviewed; 414 AA.
AC A0A0R2AGD3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN ORFNames=FC14_GL000836 {ECO:0000313|EMBL:KRM65818.1};
OS Ligilactobacillus agilis DSM 20509.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1423718 {ECO:0000313|EMBL:KRM65818.1, ECO:0000313|Proteomes:UP000051008};
RN [1] {ECO:0000313|EMBL:KRM65818.1, ECO:0000313|Proteomes:UP000051008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20509 {ECO:0000313|EMBL:KRM65818.1,
RC ECO:0000313|Proteomes:UP000051008};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594, ECO:0000256|RuleBase:RU362026}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM65818.1}.
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DR EMBL; AYYP01000010; KRM65818.1; -; Genomic_DNA.
DR RefSeq; WP_056975858.1; NZ_AYYP01000010.1.
DR AlphaFoldDB; A0A0R2AGD3; -.
DR PATRIC; fig|1423718.3.peg.873; -.
DR OrthoDB; 9800801at2; -.
DR Proteomes; UP000051008; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR CDD; cd16401; ParB_N_like_MT; 1.
DR Gene3D; 3.90.1530.10; Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR015840; DNA_MeTrfase_ParB.
DR InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF33; TYPE II METHYLTRANSFERASE M.MJAV; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR Pfam; PF02195; ParBc; 1.
DR PIRSF; PIRSF036758; Aden_M_ParB; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SMART; SM00470; ParB; 1.
DR SUPFAM; SSF110849; ParB/Sulfiredoxin; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KRM65818.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051008};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 4..93
FT /note="ParB/Sulfiredoxin"
FT /evidence="ECO:0000259|SMART:SM00470"
SQ SEQUENCE 414 AA; 47095 MW; 62F8EAD65D302163 CRC64;
MLIEKIKTEL LIPADYNPRK DLKPGDPEYE KLKRSLEEFG YVEPVIWNKT TGRVVGGHQR
LKILLNMGME EVDCVVVEMN EEKEKALNIA LNKINGDWDR EKLALLITDL NAADFDVSLT
GFDPGELDDL FKDTLKDKIR EDDFDVDSEL SKPAVSRLGD VWILGKHRLV CGDSTKKETY
NILMEGKVAN LVVTDPPYNV NYEGTAGKIK NDNMANDAFY QFLLDAFKNI ESVLASDGSI
YVFHADTEGL NFRKAFVDAG FYLSGTCIWK KQSLVLGRSP YQWQHEPVLF GWKKKGKHLW
YSDRKQSTIW EFDKPKKNAD HPTMKPIALI AYPIMNSSLT NSIVLDPFGG SGSTLIACEQ
TDRICYTIEL DEKYCDVIVK RYIEQVGTDK EVYVIREKEK IPFNVAATSS DELD
//
