ID A0A0R2CIM9_9LACO Unreviewed; 653 AA.
AC A0A0R2CIM9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:KRM87926.1};
GN ORFNames=FD19_GL000205 {ECO:0000313|EMBL:KRM87926.1};
OS Lacticaseibacillus thailandensis DSM 22698 = JCM 13996.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1423810 {ECO:0000313|EMBL:KRM87926.1, ECO:0000313|Proteomes:UP000051789};
RN [1] {ECO:0000313|EMBL:KRM87926.1, ECO:0000313|Proteomes:UP000051789}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22698 {ECO:0000313|EMBL:KRM87926.1,
RC ECO:0000313|Proteomes:UP000051789};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM87926.1}.
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DR EMBL; AYZK01000001; KRM87926.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2CIM9; -.
DR STRING; 1423810.FD19_GL000205; -.
DR PATRIC; fig|1423810.4.peg.209; -.
DR Proteomes; UP000051789; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 2.20.70.70; -; 1.
DR Gene3D; 3.30.70.2110; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:KRM87926.1};
KW Cell division {ECO:0000313|EMBL:KRM87926.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000051789};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 536..596
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 597..653
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 653 AA; 69449 MW; 1E284F0CF2CE2F66 CRC64;
MLQAQRGSIV DANGNTIATA SKTYSIYAVL QPLYSGDKEK LVKDKEKTAT MLAKYLPMAK
DKILVYLNPT SSKTKQVEFG SAGSGLSLAI KQQISRLKLP GIHFTSESSR LYEDNVFASH
IIGQTTVEGS GTSAKIVGTM GLEKYFNKLL AGKNGHTSSQ VDNYGYQLST SKAKTVPAKN
GGTVYTTLNS NLQNYLESLM SKVQSEYKPT EMTATLMNAK TGAIIAASQR PTFSLQTGDG
VSDMWRNALV QDAYEPGSVM KIMTLSAAIN SGHYNPNEYY QSGSIKVGGT TLYDWNRNGW
GTIPLSQAFT RSSNVGMVKL EQEMGGATWH HYLKKFGFGQ KTGVTLPDES SGTLSFSNAT
TQATTAYGQG IDVTVMQMLQ AMSAVANNGV MLRPRIISKT VSANGTVTKY GKQTEGRIIK
TSTAKAVRKA MVKVVQSSIG TGSAYKMNGV DVGVKTGTAQ IAGSNGYLTG ASNYIFSVAG
MVPSKNPKYL LYITLKQPQN YTKAPEEMMA EIFKPLITRA LALDAASDDA ANATTDSTTT
KMVSVTNKST TTAQSTLSNA GYHVATVGTG NKVVQQLPVA GQTTLNGSRV ILLTNGAMTM
PDVSGWSKSD VLKLAQITGK KFKLKGSGYA SAQSINAGAL IPDTGGTITF TAQ
//
