ID A0A0R2CLG6_9LACO Unreviewed; 962 AA.
AC A0A0R2CLG6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=DNA RNA helicase {ECO:0000313|EMBL:KRM92138.1};
GN ORFNames=FC80_GL000321 {ECO:0000313|EMBL:KRM92138.1};
OS Liquorilactobacillus cacaonum DSM 21116.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Liquorilactobacillus.
OX NCBI_TaxID=1423729 {ECO:0000313|EMBL:KRM92138.1, ECO:0000313|Proteomes:UP000051131};
RN [1] {ECO:0000313|EMBL:KRM92138.1, ECO:0000313|Proteomes:UP000051131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21116 {ECO:0000313|EMBL:KRM92138.1,
RC ECO:0000313|Proteomes:UP000051131};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM92138.1}.
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DR EMBL; AYZE01000008; KRM92138.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2CLG6; -.
DR STRING; 1423729.FC80_GL000321; -.
DR PATRIC; fig|1423729.3.peg.323; -.
DR OrthoDB; 9802848at2; -.
DR Proteomes; UP000051131; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd09204; PLDc_N_DEXD_b2; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR021835; DUF3427.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025202; PLD-like_dom.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF11907; DUF3427; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:KRM92138.1};
KW Helicase {ECO:0000313|EMBL:KRM92138.1};
KW Hydrolase {ECO:0000313|EMBL:KRM92138.1};
KW Nucleotide-binding {ECO:0000313|EMBL:KRM92138.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051131}.
FT DOMAIN 231..383
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 435..581
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 962 AA; 111097 MW; BA3564C0431740BA CRC64;
MENEDIKREL SLATTFGFLD NHQSGATSEL LPQLVSNEPN DTLWEHIRYE LQTCQSFSFA
IAFITEDALT PLKVILADLA TKKITGMILT SNYLMFNQPK VFTELLKIPN ITVRVVTREG
FHAKGYFFEH HDYYSLIIGS SNLTRAALLR NVEWNLHFSA LKTGAVTKQI LNQFNNEWQQ
ATMLTEQWIE EYRRLFEANQ MAKSRVTIEN KFVNKIVPNR MQSAALKELA DLRKIGEKKG
LVISATGTGK TYLAALDVRQ VQPKRMLFVV HREQILQKAL DGFKRVLGGK DSDYGILSGN
RHEEHAKYLF ATLQTISKKE VLESFTPNQF DYLLIDEAHR SGSVSYRRIL NYFTPIFCLG
MTATPERTDD YSIYQLFDYN IAYEIRLHDA LKEKMLTPFH YVGIQDYEFE GRMIDDKTPL
RLLVTKQRVN YVLKQLEYYG YSGTQVHGLV FCSNVIEADE VAQYLTKNGH PAVKLDGSDS
IKQRNQVVSQ LEQGQLEYIV TVDIFNEGID IPCINQVVML RNTQSSIVFI QQLGRGLRKY
KGKEFLTIID FIGNYKNNYL IPTALTGDIS RSKDNARADL ALQPILGLST INFTEVARQK
IYEAIQVAKL DSFATLRADY QELKQKLGRI PLLLDFQRVG GIDAEVFADN SQLDSYATFL
KKMKEQVDLS EYEGQVLSFV TKELINGMRR HELLLLKLLL KKKVKDQDFL QILQENNCYL
NLEVIESVTN ILSLNFFDIK SGKDNKAEKY GKRPIVKHEN GEYRFNSKIE ESLKNSDIFY
KLFIDVVATG LNKANNFNAK QPFTYYQKYS RKDVCRLLNW SKDVSAPMYG YRVGEDECPI
FITYEKDNPE KNRSARYENE FFNTGLIKWY TRSPRHIDSK EVQQLLAHDC NMNFKVKIRL
FLKKSDAEGK KFYYLGDAQV DLDSVREQLI QQVGKKPRAV VSMNLKINEP IKYGHFIDIT
KR
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