ID A0A0R2CVX6_9LACO Unreviewed; 381 AA.
AC A0A0R2CVX6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=rRNA (Guanine-N(2)-)-methyltransferase {ECO:0000313|EMBL:KRM93844.1};
GN ORFNames=FC56_GL000563 {ECO:0000313|EMBL:KRM93844.1};
OS Lentilactobacillus senioris DSM 24302 = JCM 17472.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lentilactobacillus.
OX NCBI_TaxID=1423802 {ECO:0000313|EMBL:KRM93844.1, ECO:0000313|Proteomes:UP000051256};
RN [1] {ECO:0000313|EMBL:KRM93844.1, ECO:0000313|Proteomes:UP000051256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24302 {ECO:0000313|EMBL:KRM93844.1,
RC ECO:0000313|Proteomes:UP000051256};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM93844.1}.
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DR EMBL; AYZR01000008; KRM93844.1; -; Genomic_DNA.
DR RefSeq; WP_056978337.1; NZ_AYZR01000008.1.
DR AlphaFoldDB; A0A0R2CVX6; -.
DR STRING; 1423802.FC56_GL000563; -.
DR PATRIC; fig|1423802.4.peg.573; -.
DR Proteomes; UP000051256; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KRM93844.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051256};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:KRM93844.1}.
FT DOMAIN 43..154
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 381 AA; 42935 MW; 6E1826CEB67FF3DF CRC64;
MEFNLIATCA AGIEALVGKE LRDLGYETQV ENGRVRFTGT EKDIIQTNLW LRTADRIKIV
VTEFPATTFE ELFENTKAIK WETMLPMDAA FPVEGRSHNS KLHSVPDVQR IVKKAIVDEL
SEAYHRRGRL AETGATYPLE IVMNKDQAMI TLDTTGPSLF KRGYRVEKGP APLKENMAAA
LVMLTNWYPD MPFLDPFCGS GTIAIEAALI ARNIAPGFNR DFAFEAWDLI DDQLTQQLRD
EADSKADYDS ELTIMASDID GSMIEIAKKN ALEAGVFADI NFKQVAVADF KTDLINGVVV
GNPPYGERMA DKDKVTQLYR QIGEVFKPMT SWSKYFLTSD LDFEAAYGQK ATKKRKLYNG
ALRVDYYQYW GKKIRPQQTN A
//
