ID A0A0R2FB12_9LACO Unreviewed; 720 AA.
AC A0A0R2FB12;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:KRN25586.1};
GN ORFNames=FC75_GL000317 {ECO:0000313|EMBL:KRN25586.1};
OS Lacticaseibacillus camelliae DSM 22697 = JCM 13995.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1423730 {ECO:0000313|EMBL:KRN25586.1, ECO:0000313|Proteomes:UP000050865};
RN [1] {ECO:0000313|EMBL:KRN25586.1, ECO:0000313|Proteomes:UP000050865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22697 {ECO:0000313|EMBL:KRN25586.1,
RC ECO:0000313|Proteomes:UP000050865};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN25586.1}.
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DR EMBL; AYZJ01000009; KRN25586.1; -; Genomic_DNA.
DR RefSeq; WP_056988915.1; NZ_AYZJ01000009.1.
DR AlphaFoldDB; A0A0R2FB12; -.
DR STRING; 1423730.FC75_GL000317; -.
DR PATRIC; fig|1423730.4.peg.333; -.
DR Proteomes; UP000050865; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 2.20.70.70; -; 1.
DR Gene3D; 3.30.70.2110; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:KRN25586.1};
KW Cell division {ECO:0000313|EMBL:KRN25586.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000050865};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 660..718
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 720 AA; 77142 MW; 333061E4A9577FDC CRC64;
MKKKTNKRQM RARHPERNRQ RFGIFLFWLS LVALLAFVCR FAYVAVVGSV DSKHLAAYRA
SQYARKTALQ AKRGSIVDRN GQAIAEDAST YTIYAIIDQN YTQNGKKLYV SDKAKTAAVL
AKYLPLSEAK ILAYLNPKKK TFQVEFGAAG TRLSLSTRKE IEAEHLPGIH FTDSPSRLYP
NGVFASYTVG LTQTNATNKN QPLVGVMGLE KEFNAQLAGT NGYQTAQVDN YGYRLPKAKV
KTKPAKNGGT VKSTLDSSLQ SYLETLLASV QTKYKQASVT GVVMNAKTGE ILAAGQRPTF
DPSTMEGLEQ GSSWQNMLVE DTYEPGSVMK VFNLAGAIQS GTFQPNTYYN SSGVKVASTT
IHDWNHVGFG EIPFSQALPR SSNVGFVHIV QQMGEANQAK TLKDFGFGQK TGITLPNEAT
GGYNLSNAVT RAVMGYGQSI NVTQMQILQA ATAIANKGTM VQPRVVTKVT DPDGKVINYK
RKVVGHPISA TTAETVLDEM RDTINKPYGT GVTYKIAGAD VAAKTGTANI ANPKGGYLPG
ETNQLHSLLA MAPASDPQFI VYLTLKQNTA MTTPAVNVLN TIYHPLMTRL LALDAGNTAT
PAAETVTVPA AVNDSLTAAT AALNKKALTA SVVGTGNRIV QQLPAAGTQA LRSARVVLLT
NGAMTMPDVS GWSKSDVLKL AQLTGKKFKL QGAGYASAQS LKAGSLLGTG TVTVTFQKTD
//
