ID A0A0R2RXH0_9FLAO Unreviewed; 795 AA.
AC A0A0R2RXH0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=DNA mismatch repair protein MutS {ECO:0000313|EMBL:KRO67046.1};
DE Flags: Fragment;
GN ORFNames=ABR84_02500 {ECO:0000313|EMBL:KRO67046.1};
OS Cryomorphaceae bacterium BACL21 MAG-121220-bin10.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Cryomorphaceae.
OX NCBI_TaxID=1655592 {ECO:0000313|EMBL:KRO67046.1, ECO:0000313|Proteomes:UP000051758};
RN [1] {ECO:0000313|EMBL:KRO67046.1, ECO:0000313|Proteomes:UP000051758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BACL21 MAG-121220-bin10 {ECO:0000313|EMBL:KRO67046.1};
RA Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA Andersson A.F.;
RT "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC {ECO:0000256|RuleBase:RU003756}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO67046.1}.
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DR EMBL; LICC01000022; KRO67046.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2RXH0; -.
DR STRING; 1655592.ABR84_02500; -.
DR Proteomes; UP000051758; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756}.
FT DOMAIN 612..628
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRO67046.1"
SQ SEQUENCE 795 AA; 88683 MW; 9B2B89FEDA802D5C CRC64;
LVMAGCRVAI CDQLEDPKQT KTIVKRGVTE LITPGVALND DILQSKTNNF LAAVHLTDAI
CGVSFLDVST GEFLMAEGPL QTIDALLQNF NPSEVLFNKQ QRKLVNTHFG HRLHCFFLEE
WVFQPDYTHD LLLGHFKTKS LKGFGLQDRT MGGIAAGAVM HYLGETQHHR LDHITKISRI
AQDTYVWMDQ FTMRNLELHQ GQSSNAATLM GVMDHTISPM GGRLLKRWLA LPLKTVAAIK
DRQDIVRYWV AQQQQRAELR HSLKSVGDLE RLVSKTATGK INPREVVMLG RSLRATESLK
DLAATSNNKA LEALSAQIDP CTALCLKIEQ TLDPEAAVHW NKGNVIAQGV NVALDELRSI
AFGGKEHLQK MLEGHQEETG ITSLKIASNN VFGYYIEVRN AHKDKVPPQW IRKQTLVNAE
RYITEELKEY ESKIYGAEER ISGLEQTLFL ALIQEILPYV SAIQQTAQAL AQLDCLSGFA
ELAQRSNYVC PEFNDSFDLA IKQGRHPVIE TQLSEDTPYI ANDVFLDRST QQMIMITGPN
MSGKSALLRQ TALIVIMAQM GSYVPAKAVT MGVVDKIFTR VGASDNISMG ESTFMVEMNE
TASILNNVSE RSLILLDEIG RGTSTYDGIS IAWSISEFLH EHPTQAKTLF ATHYHELNDM
SETFERIKNY NVSVKELKDT VLFMRTLVPG GSEHSFGIHV AKMAGMPKRV ISRAEEILKR
LEASHGAKER HAEVKAAADS EMQLSFFQLD DPLLEEIKQR IVSMDIDGLT PVAALNALND
IKRMLVKGSD PEGKK
//
