ID   A0A0R2RZD1_9FLAO        Unreviewed;       858 AA.
AC   A0A0R2RZD1;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Peptidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ABR84_03880 {ECO:0000313|EMBL:KRO67868.1};
OS   Cryomorphaceae bacterium BACL21 MAG-121220-bin10.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Cryomorphaceae.
OX   NCBI_TaxID=1655592 {ECO:0000313|EMBL:KRO67868.1, ECO:0000313|Proteomes:UP000051758};
RN   [1] {ECO:0000313|EMBL:KRO67868.1, ECO:0000313|Proteomes:UP000051758}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BACL21 MAG-121220-bin10 {ECO:0000313|EMBL:KRO67868.1};
RA   Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA   Andersson A.F.;
RT   "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the peptidase M36 family.
CC       {ECO:0000256|ARBA:ARBA00006006}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRO67868.1}.
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DR   EMBL; LICC01000002; KRO67868.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R2RZD1; -.
DR   STRING; 1655592.ABR84_03880; -.
DR   Proteomes; UP000051758; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09596; M36; 1.
DR   CDD; cd04818; PA_subtilisin_1; 1.
DR   Gene3D; 3.10.170.10; -; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR001842; Peptidase_M36.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   InterPro; IPR026444; Secre_tail.
DR   NCBIfam; TIGR04183; Por_Secre_tail; 1.
DR   NCBIfam; NF038113; T9SSA_dep_M36; 1.
DR   PANTHER; PTHR33478; EXTRACELLULAR METALLOPROTEINASE MEP; 1.
DR   PANTHER; PTHR33478:SF1; EXTRACELLULAR METALLOPROTEINASE MEP; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF02128; Peptidase_M36; 1.
DR   Pfam; PF18962; Por_Secre_tail; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
PE   3: Inferred from homology;
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..858
FT                   /note="Peptidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5006423133"
FT   DOMAIN          456..535
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          785..857
FT                   /note="Secretion system C-terminal sorting"
FT                   /evidence="ECO:0000259|Pfam:PF18962"
FT   REGION          354..389
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        354..388
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   858 AA;  91902 MW;  51CE675A2ED95AFA CRC64;
     MKKLLLLAGF LTFNFGFAQD EARVIREYLG QERAQFNLTA SDVQSPALKS SSFSQSMNVT
     TAYANQTHQG IEVFNTTSRF AIRDGQVVSA KLSFASDVAS KINTTAPSIS ARTAILKAAQ
     ALGLQAPAQL EELSAEDNTY VFKATDLSLN TIPVALTYQH LSDSQYVLAW DLSLYIMDAT
     HYYSVRIDAQ NGALIDTKDW VQHCDFGQGI HEGHAAESIL FAPAKSERAM AMVDAQYRVF
     PMPLSNPFDG DDQVVTSPEN LDASPFGWHD TDGVVGAEHT VTRGNNVWAR EDIAGTNNGG
     ASPEGGVDLI FDFPYGLPQA PENFTDAATV NLFYWNNIIH DVTYQYGFDE ESGNFQENNY
     GNPGNGGDSV NADAQDGSGT NNANFATPPD GGNPRMQMFI WTGSAGPIEL LTINNGPLAG
     VYSGVPAGFG GAMPNPALTE DIVLIEDDNS GTSTDTADGC DPIVNGLDLA GKIVVIRRGI
     CEFGFKALAA ENEGALAVIM VNNVAGDPIL MGAGAVGAQV TIPLFMVSDV DGEAIIAELL
     TGNVINGTID GGATPPSIDG DLDNEIIAHE YGHGVSNRLT GGPVNTSCLG NAEQMGEGWS
     DYLGLIMTMQ TGDQASDVRG LAAYASGNPN GIREAPYSTD FSVNDYTYAD TNANVSQPHG
     IGFVWASMLW DLTWDLIDLY GFDEDIYNGT AGNNIAFQLV MDGMKLQPCS PGFVDGRDAI
     LEADELANNG IHRCLIWEAF ARRGLGFSAD QGNSNSRSDQ TEAFDIPESC NLSTIDSNYD
     NNFNIYPNPT RGLIQINSVV DLGATVVSIY DMNGRRVWNN TLELGHHTQI DASALSSGIY
     LIKIEGGNYS HTSKLIIR
//