ID A0A0R2XAS3_9BACT Unreviewed; 699 AA.
AC A0A0R2XAS3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=ABS33_04890 {ECO:0000313|EMBL:KRP33304.1};
OS Verrucomicrobia subdivision 6 bacterium BACL9 MAG-120924-bin69.
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Verrucomicrobia subdivision 6.
OX NCBI_TaxID=1655635 {ECO:0000313|EMBL:KRP33304.1, ECO:0000313|Proteomes:UP000051220};
RN [1] {ECO:0000313|EMBL:KRP33304.1, ECO:0000313|Proteomes:UP000051220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BACL9 MAG-120924-bin69 {ECO:0000313|EMBL:KRP33304.1};
RA Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA Andersson A.F.;
RT "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRP33304.1}.
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DR EMBL; LIDN01000151; KRP33304.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2XAS3; -.
DR Proteomes; UP000051220; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 439..575
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 699 AA; 76724 MW; 639A1D971C34855A CRC64;
MAKTAKKEAS TRRLILIGIC VGAGLLLGLL NLIQFKPLLE AELYTRDLRV RFGQTAPLSP
EIVFITIDKP TYQDILTEEE IAADPALAEM STGSWPWRRS VWASVIQRIS QAGAKVVGLD
LMFPTPKDGD QELLQIMDQE GSRAVLGGTF EEVSNAGRTS VQLTLPAALA SIGAPEISNE
NPAGRVGFVN LWPEKDGIVR SADYRRQFQD IPAVSLACRM LEKAGYADRI PATGSGILRF
AGPPNFNYKA IPVYQLFVPA TWEKVFENGA KLKDKIVLVG PYGNWSKDVI RTPYPNPMPG
PEVHLAALGA ALSGSFLTLP PFWTTPALIA SAALLAFLLI LATKQPILRL ILLVAIGVGY
AVLTFLIQDK LSLILPAVNP VLTLLFGGIG CLGYEFVLEQ REKRRVSGMF STMVSPEVLS
YMQADPDRFR LTGEKRMVSI FFSDLAGFTT ISESVSAEDL AKILNRYLTP MSDLVTKYGG
YIDKYSGDAI MADFGVPVWV DPDPNSHAWK ACWSALEQQE RLQSLKQELK AEYGCDIDAR
MGINTGEVAA GNMGSDKKFQ YTVMGDAVNQ AARFEPANKP FDTHIMIGGK TYEMAKEKIE
ARFLANMIVK GKTEPVPCYE LLAKKGELSE TKARVVQLFE EGWKLHAAKK FPQAIAKFDE
ALAVEVNDGP SKAYKKICEG FLKSPPPDSW AGEYIQTSK
//
