ID A0A0R2XRJ3_9BACT Unreviewed; 708 AA.
AC A0A0R2XRJ3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=ABS34_06780 {ECO:0000313|EMBL:KRP36571.1};
OS Opitutaceae bacterium BACL24 MAG-120322-bin51.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=1655636 {ECO:0000313|EMBL:KRP36571.1, ECO:0000313|Proteomes:UP000054041};
RN [1] {ECO:0000313|EMBL:KRP36571.1, ECO:0000313|Proteomes:UP000054041}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BACL24 MAG-120322-bin51 {ECO:0000313|EMBL:KRP36571.1};
RA Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA Andersson A.F.;
RT "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRP36571.1}.
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DR EMBL; LIDO01000070; KRP36571.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2XRJ3; -.
DR Proteomes; UP000054041; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 24..192
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 218..378
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 634..708
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 708 AA; 77512 MW; 0EC1D617EF9E5AB9 CRC64;
MTPEDALQKY FGMPAFREPQ GDIIRAVLEK KDTLVVMPTG GGKSLCFQLP ALLLPGVTLV
VSPLIALMKD QVDALQARGL PAGLLNSSQT LEQQHETLDA IRNRTLKLVY VAPERFRSSA
FLNALPKDAI SLFAIDEAHC LSQWGHDFRP DYMRLGEARK AIGNPPCIAL TATATPDVQR
DIKKSLEMEA PAEFVAGFAR DNLSFRVRQT NSEHDKMQAL QALIKQHTTG IIYCATRKSV
DAVAGKIEHL TSSVIRYHGG LSDRDRTTAQ ERFMTGGANI VVATNAFGMG IDRSDIRFVC
HYEMPGSVEA YYQEGGRAGR DGQPSVCEML FSYADKRVQD FFIEGANPGK QLIAEIFDLL
CAESDAQHEV RLPVDDLCER VGRKVNPMAV STAISVLARQ GWIDRFDIPG TRLKGTRIKQ
LGQSGNSLPI DGAALAVKAA RDEERLKTVI NFSYAQSCRQ KWILDYFGER NGANCNRCDN
CKQAKNSASR APSKDEFTLV QKALSGVARM SRNLGSDEWA PRFGKRKIIQ CLLGSQSTAI
RDSGLDQLST HGILKREGSA FVDALFECLE RAGLVQTVVE GTYPLLQLMP SGARVMRGAE
SIDLELPERT AGAVSQKADS ATARSKRQGA ETGGILDRRL YGLLVGHRAK MAAKTGKPAF
TVFPNSVLVE LANQKPQTEQ EALEIKGIGP AKLKSVLPEF LEVIQANS
//
