ID A0A0R3S6F9_9BILA Unreviewed; 584 AA.
AC A0A0R3S6F9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS Elaeophora elaphi.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Elaeophora.
OX NCBI_TaxID=1147741 {ECO:0000313|Proteomes:UP000050640, ECO:0000313|WBParaSite:EEL_0001038101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EEL_0001038101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC multimeric enzyme that catalyzes the translocation of protons across
CC the membranes. Required for assembly and activity of the V-ATPase.
CC {ECO:0000256|RuleBase:RU361189}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361189}.
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DR AlphaFoldDB; A0A0R3S6F9; -.
DR STRING; 1147741.A0A0R3S6F9; -.
DR WBParaSite; EEL_0001038101-mRNA-1; EEL_0001038101-mRNA-1; EEL_0001038101.
DR Proteomes; UP000050640; Unplaced.
DR GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR PANTHER; PTHR11629:SF73; V-TYPE PROTON ATPASE 116 KDA SUBUNIT A 2; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 406..430
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 451..469
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 549..572
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT COILED 58..117
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 584 AA; 67696 MW; DAD2F0C2DBDE7670 CRC64;
MGSLYRSEQM RFCQMIVQKD AAFSCVAELG KHPYVQFKDL NANMNPFQRM YLRDIQRFEE
LERKLRFLDA QIRKDDIEVN DDVSRDDTYE VMAPHELNQL EGTLIDLERD VISMNENNII
LKRNYLELKE WEAILEKTDQ FFEEGISDVA MQEIEAVQDD AALVLKSGKE PIGFLAGVIN
RDRVNAFEKV LWRACHKTAF VRTTDIEEEL ENPDSGEMCS KSVFLVFYKS ERLRIIIEKV
CEGFKAKLHS SCPKNSKDRH AAARDVKARI SDMRTVLGQT QEHRYKVLQA ASNSVRQWQK
EVRMQKSVYY TLNLFTFDAI GKFFVAECWV PYADLENVRL ALEEGVRKSG SSVRPALNLL
ETTEEPPTYN RVNKFTRVFQ TIVDSYGIAS YLEINPAPYT IITFPFIFSC MFGDLGHGII
MLLAGLWMVL REKNLAARNI KDEIFDMFYG GRYIVLLMGI FSIHAGFLYN DIFAKSFNLF
GSKWRNPFPK KEIESWDSQS VLTNKEILID LPPSQSYMHD SGPYWFGVDP IWNLAENRLN
FSNSLKMKLS VILGIAQMTF GVFLSLLNYM YVACKIFPDY CQHY
//
