ID A0A0R3W203_TAEAS Unreviewed; 2569 AA.
AC A0A0R3W203;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=BPTI/Kunitz inhibitor domain-containing protein {ECO:0000313|WBParaSite:TASK_0000380301-mRNA-1};
GN ORFNames=TASK_LOCUS3804 {ECO:0000313|EMBL:VDK32372.1};
OS Taenia asiatica (Asian tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000380301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TASK_0000380301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK32372.1, ECO:0000313|Proteomes:UP000282613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; UYRS01018314; VDK32372.1; -; Genomic_DNA.
DR STRING; 60517.A0A0R3W203; -.
DR WBParaSite; TASK_0000380301-mRNA-1; TASK_0000380301-mRNA-1; TASK_0000380301.
DR Proteomes; UP000046400; Unplaced.
DR Proteomes; UP000282613; Unassembled WGS sequence.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00109; Kunitz-type; 4.
DR Gene3D; 2.40.155.10; Green fluorescent protein; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 4.
DR Gene3D; 2.90.20.10; Plasmodium vivax P25 domain; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR003645; Fol_N.
DR InterPro; IPR009017; GFP.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR10083:SF377; BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10083; KUNITZ-TYPE PROTEASE INHIBITOR-RELATED; 1.
DR Pfam; PF00014; Kunitz_BPTI; 4.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00181; EGF; 21.
DR SMART; SM00274; FOLN; 7.
DR SMART; SM00409; IG; 1.
DR SMART; SM00131; KU; 4.
DR SUPFAM; SSF57362; BPTI-like; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF63825; YWTD domain; 1.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 3.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 4.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000282613}.
FT DOMAIN 738..788
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 1055..1105
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 1221..1271
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 1299..1349
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 1962..1999
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2011..2047
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2082..2173
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DISULFID 1970..1987
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2015..2025
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 2569 AA; 283183 MW; D447C1520439D425 CRC64;
MRPLTRKCSP QTSENTVSEA GYTKMRLSLL TALAILLLNA ASPARAFDSR LSIGSALDTS
GFTMQTEFPA SFGEQVHMFQ FPFQIYGKQI DQIKVSLRFY RLQQFNAFAL AAGNKVWNSD
AAKVETETMG CFVCFKRRDL DVNEVESNTC VWDHVSRIGN IIDTAAPDSK KGFVADYIFS
ITWENMGCFP RSHPLVGPPS FIHLQICPYP YLPLLHKEVS KILVNKFTLA LLRMEEKSYA
VFQYEDIQWT ADHSTSSLPP EGGIFVHGVA TPQLPRSNMH IEPNVWNEYT GISKMASIFY
LLHLLSRNMY DCPSSCPIDR ESNIAVPGEW LFPLHEGPID VDVAAQSKIR MATEGFLETS
AKNCLNMTGS SAKTTSVSES STTAFPYSYT VTKTDSAYTT DYSSAQTKST LDDNYSDVSQ
TTDLEQQFER CDSSSCANSM ADCFYFDGHK CCVCLPNYYG GGEEGCWSAA PEKPRRIYLD
GELLINLGTT DGKSVSAPIF LDTEVRRGET IRSQSGIHDA PQNFPSLYAI TPIFSILNSF
LALPRSQDSD RTTSRVFNIF SLTAGFTVPF NFTFTLDVSN YGRLAIRGNL RRSSSTEDIF
RGSLNMEVTP DGQFRPLSSR LVGSDGLLQA ENGLDRRIVY EKLGAGKVKF GPQTYNLRSE
EGQTISVQLY GGGEVAVEEG SCLLAENSLM AKGQKFTVKM DAQGYCREDC RPNYGCSLYC
MDMPVYFGED SGQSEDVCSL PTVVGPCTAN IQRYTYNRST GRCEAFYYGG CEGNKNNFES
LDECQRLCES SYQQVPFLHK IALPSLEDPC TNVRCGLNAY CASGYCYCNA GYRGDANTEC
RPASSGAPLF IFRRAFPDCT YNPSNNCCKA FHCGCCESET SGFEGQDDCR WCCESSNHYD
QFADLNVNCK FDADCPLESD WDEIELVTTV ASLNHSVLCR DVSCGYNARC REGRCECEEG
YSGDPYRECQ WTGDPCQNVR CGANAYCSNG QCFCRRGYEG DPQIECRPSY EDPCRGLRCG
YYAHCSDGRC ECDEGYSGDP YRECQWTGGQ SDDICNLPTE VGPCNEVILR YTYNRSIGRC
EAFYYGGCQG NANNFDSLEK CQQRCEALGQ QGESIADLHL FSQTIKDPCA HIRCGHNAHC
VNGYCYCNPG YEGDGNTYCR PTSSETYNYS FILGNPCESV RCGENAECLE GQCKCMEGYY
GDPFHACRPI GSEMPSSNPK CQLPIDSGQC FDRLEKYGYD SRTGRCEKFL YTGCLGNENR
FDTLEKCERE CGAAQNRCKL VFPVTALNKA PKNAVPDKCF LPLITGTCGN THTRFGFYPP
TQRCEEYNYS GCGGNENRFE TRLDCETVCN DPCEGVRCGY NARCVEGRCV CEPGFSGDPN
YECKAEKTDK CDGVRCGANA RCQDGYCVCE AGHSGDPYRE CQPVGRFEHE PHLLTALTSY
AFLMLAVVSV AATMPDVLRA GANVSPVMRE TRTPNAGPVN ADLCKVLGCD TNAVCLNGEC
KCRQGFTGDP YEGCVKTQYL KPAVRMPRDS CHKVACGVGA FCDLGTCHCP EGSRGNPYIK
CQFDSTFLGK LYAPEMLPSK VGSPAQHNRC NGVQCASNAY CESGYCRCNP GYAGDGFVEC
HYQGSCANVQ CGTNAHCVNG RCVCWPGYTG DPDRRCDPAV APRPELCGNI YCHEKARCHS
GTCYCEYGYA GDGVRVCEKV EEDLCKRVQC AENAECEAGL CQCKPGYKGD GFSECTPMEV
DPSSCNGRYC GANAECRDGV CVCVPDYTGD PYDICTRKRP LPDSCHGIEC GSNAYCQDGG
CVCFEGFEGD PNLACKPIYD PSCVGIRCGA NAYCRGGRCV CPQGYVGDAN QVCYPVWVVF
QTKSVLLNET LLSKVLRVLM PVITLRATRT QPVPKGSVNA TTDSKEMASL TAGLRILVRT
VRPFNLANLC DCRGLPASMT GCSNGKCRCM PGFKMNRDNY CEECRGSGEC AANAQCIYDR
QIQHYRCACD AGFLGDGAIA CISGAVANRT EAAQCRVPCH RFATCDEYDG RCKCRSGFIG
NGYTYCDFDC SQCHAEAQCV PESNQCVCPP GFTGDGIRIC RPATSQGLFT LRIVKDSETI
RVREGSGALT LRCVLSGDVR NVQARWLTPG DVGRTDEQTT HEGRELWLTI GQPSPKDSGL
YVCQASRVSD TINVIVEPQQ RSILCLIPTK LSIIVGEEKL SSSDFSNFLT LFPEVQTKQL
FLTSDNGILT VQTQSEPTTA AQIWHIAEAN KHKPVALALD CKTDRLIYTS DGGRALRFGN
ASVARLNQPP ELIFQDNSAK FTWIAVDPAS GNVFAIDKEN NRIVVVNPDR PNQVHTYKQL
ADRRSDRDFI AGGIAVHPGL SLVYWAQAEN SDFEKGESVI KVASMADSER VSEITRVTGA
PISMSLAVTD DVTGGGNTAG RLCWLQRRQL MPYSRTEIHC AQLEASGRAI HSKRLLKSFG
TNEEPSYGLI QDDDTIFWTS LYRKIYRSLN PSASIYVKGV CCSNGFQSMV IHNTCKRSMT
NTCSYENGRC RYFCLPGGRE MAHVCRCPDD QPNCIAEHAR SRFLGYPYS
//
