ID A0A0R3W9I1_TAEAS Unreviewed; 619 AA.
AC A0A0R3W9I1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN ORFNames=TASK_LOCUS7110 {ECO:0000313|EMBL:VDK37882.1};
OS Taenia asiatica (Asian tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000710901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TASK_0000710901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK37882.1, ECO:0000313|Proteomes:UP000282613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|RuleBase:RU000675};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR EMBL; UYRS01018575; VDK37882.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3W9I1; -.
DR STRING; 60517.A0A0R3W9I1; -.
DR WBParaSite; TASK_0000710901-mRNA-1; TASK_0000710901-mRNA-1; TASK_0000710901.
DR Proteomes; UP000046400; Unplaced.
DR Proteomes; UP000282613; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW Reference proteome {ECO:0000313|Proteomes:UP000282613}.
FT DOMAIN 25..344
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 388..502
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 528..586
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 173
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 256
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 619 AA; 69741 MW; 7F3C660604E064EB CRC64;
MSNNLVAVFG KSSRTFSIDR ENGVFLKDGE PFRYISGSLH YFRIPRIYWE DRLVKAKSAG
LDAIQIYIPW NYHEPRPGEY IFENERDVVE FIELAQKIGL LVLVRAGPYI CAEWDFGGLP
PWLMSSNPRL NLRSSDPEYI KPVIRWFGQL LPKLKPLIYQ NGGPIIMIQL ENEYGSYITC
DQEYLSALYE YARYVLGDEI ILYTTDGSST LQLKCGSSDR RLFATVDFGI DGAKHPAETF
KALEQFQPHG PLVNSEYYSG WLDHWGEKRH VVDATALAWG ALNLWNVSHR VSFNIYMFHG
GTNFGLWNGA NSPNQFIITS YDYDAPISEA GDITTKYLVL QDLFYKLKQQ VQPPPPVNIS
KADYGKIGLK FFSHLLYELQ EGISSVKPLY MEALGQYQGL MAYTTHLERD EGKANLTFEN
VKDIGLVFTT DLQAKSIIFH GSVSGRASLN ITMDKEHSFL TVVTECRGHI NYGPLMAGDV
KGIVGRVLLD GKELLNWMMK ALDFRAVNPP GLMRPDTEGT AFPAPGMIYK GVFQVPSPPM
DTFAVVTGFT RGFLAVNGHI VGRYYPSAGP QVSLYVPTSM LIPGENVVSI LELQNVEPAC
LKNVSFCFVS FRDYPVWLN
//
