ID A0A0S1Y5K5_9BORD Unreviewed; 774 AA.
AC A0A0S1Y5K5;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ASB57_21390 {ECO:0000313|EMBL:ALM85190.1};
OS Bordetella sp. N.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=1746199 {ECO:0000313|EMBL:ALM85190.1, ECO:0000313|Proteomes:UP000064621};
RN [1] {ECO:0000313|EMBL:ALM85190.1, ECO:0000313|Proteomes:UP000064621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N {ECO:0000313|EMBL:ALM85190.1,
RC ECO:0000313|Proteomes:UP000064621};
RA Hou L.;
RT "Draft genome of Bordetella sp. N.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP013111; ALM85190.1; -; Genomic_DNA.
DR RefSeq; WP_057654041.1; NZ_CP013111.1.
DR AlphaFoldDB; A0A0S1Y5K5; -.
DR STRING; 1746199.ASB57_21390; -.
DR OrthoDB; 9815750at2; -.
DR Proteomes; UP000064621; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR017232; NtrY.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PIRSF; PIRSF037532; STHK_NtrY; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ALM85190.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000064621};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 316..368
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 524..755
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 774 AA; 84678 MW; 4256710DFDB2E2BA CRC64;
MRKLLRFALV AGALAGVLLL GLLAWSTGNA SRFARYYDAL LILNGVVALA LFAWVLALTV
KLVRQIRRRQ FGARLTARFA LAFTLIGVVP GALIYTLSVQ FMSRSIESWF NVRVDSALEA
GLNLGRAALD SLLADLDARA RSMTAELNRA SDSNIALTLT RLREANGVQE AMVFTGTGRM
VAFSTNQYGQ LLPALPPSTV LNQLRLSRGY SAAEADDPVK GDGGGALHLR VVIPLLPNER
FDGLLGASAE PRWLQLVQPV PDQIAHNANL VQQGFRDYQE LALARLGLRK LYGITLTLAL
LVSVFTAIAV ALSLSKRLVR PLLRLAAGTQ AVGIGDFRPL PEPPERDEVG QLTRSFNAMT
RQLDEARRMV ESNRQQLERS NVYLESVLSN LSSGVLVFDE AFRVTTVNQG AQTILQTDLR
SVIGRPLETI DGMLPFTQVV RQAFTAHAAV GSERQHWQQQ FEIQLAQADA DAPAGPHAQS
LTLLARGTHL RVDGRGNGYL VVFDDITELM SANRTVAWGE VARRLAHEIK NPLTPIQLSA
ERLAMKLADR LQPADRQMLE RSTNTIVNQV SSLKHMVDDF REFARTPPAV MQRIDFNALV
ADVLSLYGWD PVEGLVRDHS NSLNLEVELA PGLPAIEGDP TQLRQVIHNL LANARDAIAG
QAEGRVRVST QLTQTPRNEG EEHRALRFTV SDTGPGFSQQ VMQRAFEPYV TTKSHGTGLG
LAIVRKIVEE HGGRIDLANR REGGARISIL LTRLAGAVDT LDASAQQQDN AATQ
//
