ID A0A0S2DBE0_LYSEN Unreviewed; 600 AA.
AC A0A0S2DBE0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Peptidase, families S8 and S53/proprotein convertase P-domain protein {ECO:0000313|EMBL:ALN55842.1};
DE SubName: Full=Serine protease {ECO:0000313|EMBL:QCW24821.1};
GN ORFNames=FE772_03165 {ECO:0000313|EMBL:QCW24821.1}, GLE_0484
GN {ECO:0000313|EMBL:ALN55842.1};
OS Lysobacter enzymogenes.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=69 {ECO:0000313|EMBL:ALN55842.1, ECO:0000313|Proteomes:UP000061569};
RN [1] {ECO:0000313|EMBL:ALN55842.1, ECO:0000313|Proteomes:UP000061569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C3 {ECO:0000313|EMBL:ALN55842.1,
RC ECO:0000313|Proteomes:UP000061569};
RA Kobayashi D.Y.;
RT "Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter
RT antibioticus ATCC 29479.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QCW24821.1, ECO:0000313|Proteomes:UP000308311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC36 {ECO:0000313|EMBL:QCW24821.1,
RC ECO:0000313|Proteomes:UP000308311};
RA Feng T.;
RT "Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically
RT Regulate the Twitching Motility of Lysobacter enzymogenes.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; CP013140; ALN55842.1; -; Genomic_DNA.
DR EMBL; CP040656; QCW24821.1; -; Genomic_DNA.
DR RefSeq; WP_057946069.1; NZ_CP040656.1.
DR AlphaFoldDB; A0A0S2DBE0; -.
DR STRING; 69.GLE_0484; -.
DR KEGG; lez:GLE_0484; -.
DR PATRIC; fig|69.6.peg.480; -.
DR OrthoDB; 9790784at2; -.
DR Proteomes; UP000061569; Chromosome.
DR Proteomes; UP000308311; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04059; Peptidases_S8_Protein_convertases_Kexins_Furin-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR034182; Kexin/furin.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR42884:SF32; EXTRACELLULAR SERINE PROTEASE; 1.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000061569};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..600
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033242112"
FT DOMAIN 467..600
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT ACT_SITE 79
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 116
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 373
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 600 AA; 62715 MW; 10834D4FE38FCFAE CRC64;
MRQDWKKQTA LCVATLAALS AGAAQAQQGD PLYRYQWHLM NYGQAVIGDT RPVSGIDIGI
DDLHDYNIRG KGVIVGVLDR GIEIAHPDIA ANMVPNGSWN FINQTHDTTP TNGQAHGMAV
GGIIGAVGWN GIGVRGVAPS ARLKSFNFLD AGGSNDQVRY AWWDGALAKD QDVSNNSWGP
TFPIFLPTIS ENELAAWENP MSATRGGRGV VYVKAAGNSF SYVGGSSFRN GENLCAANRP
AVGCSQSIFA RESNFFNVIT VAAVNAAGRR SSYSTPGASI WVSGLGGEYG WERATLAAQQ
TTPEDQAALA RLSAVNFDPA IMTTDLSGCA LGYNTNQVRP ATTWSHDNVN RLESDQSAID
NTCNYAATMN GTSAASPTVS GVVALMLQAN PKLSFRDVKY ILATTARQID PQQAPVVDAA
GNVLAAGWTV NAAGRPFSAW YGFGLADATM AVTRATGFKS LGTLLDSGWQ RAALAQAQPI
GNTAAPARAT IRIAGGAARI EGVQIGFDTS APARNAYPYV ATTVRITLIS PSGTRAIVLP
PGSLPVNDGG TLSASLASVN AFLDEPGNGD WTLEVADTAL AAGAAANANL SSFKIRVLGR
//
