ID A0A0S2W579_9FIRM Unreviewed; 434 AA.
AC A0A0S2W579;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=4-hydroxybutyrate coenzyme A transferase {ECO:0000313|EMBL:ALP94279.1};
GN ORFNames=IB211_01888c {ECO:0000313|EMBL:ALP94279.1};
OS Intestinimonas butyriciproducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Intestinimonas.
OX NCBI_TaxID=1297617 {ECO:0000313|EMBL:ALP94279.1, ECO:0000313|Proteomes:UP000064844};
RN [1] {ECO:0000313|EMBL:ALP94279.1, ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|EMBL:ALP94279.1,
RC ECO:0000313|Proteomes:UP000064844};
RX PubMed=26620920; DOI=10.1038/ncomms10062;
RA Bui T.P., Ritari J., Boeren S., de Waard P., Plugge C.M., de Vos W.M.;
RT "Production of butyrate from lysine and the Amadori product fructoselysine
RT by a human gut commensal.";
RL Nat. Commun. 6:10062-10062(2015).
RN [2] {ECO:0000313|Proteomes:UP000064844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF211 {ECO:0000313|Proteomes:UP000064844};
RA de Vos W.M., Bui N.T.P., Plugge C.M., Ritari J.;
RT "A butyrogenic pathway from the amino acid lysine in a human gut
RT commensal.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; CP011307; ALP94279.1; -; Genomic_DNA.
DR RefSeq; WP_058117850.1; NZ_CP011307.1.
DR AlphaFoldDB; A0A0S2W579; -.
DR STRING; 1297617.IB211_01888c; -.
DR KEGG; ibu:IB211_01888c; -.
DR PATRIC; fig|1297617.4.peg.1945; -.
DR Proteomes; UP000064844; Chromosome.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR21432:SF20; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR21432; ACETYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000064844};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ALP94279.1}.
FT DOMAIN 22..180
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 274..427
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 434 AA; 47122 MW; 7AF23D65945EE623 CRC64;
MTSAEIMFRQ KRTTPAGIAA QIKSGDVCCC TSALGEPEAI MNALADRAIA GELTGVQHHM
LLPCRKWRYL EPDMAGKITF VSWFTSANAR KAVKEGRADF MPNFYYEVPR FWRELVKPDV
FYAMVSPMDK HGYFSFGVGA SEGRAQMCRA AKIFLEVNPR MPRVLGDNFV HISEVDALCE
SSNALPTLPD APLGEKDLKI GAYVAERISD GATIQLGIGS IPNAVGKNLV DKKDLGIHSE
MFTDSMVDLI ECGAVTNRKK NIDIGKSVAS FAVGSQRMYD FLDDNPGILF APVSYVNDPR
VISQNNDMIS INACLQLDLV GQVCSESVGP TNISGTGGQL DFVRGANWSK GGHTFICTYS
TAKDDTMSSI VPTLAPGAHV STPKGDVDCI VTEYGIASLK GKTASQRAKA LIEIAHPKFR
EELTQAAKKM NLMI
//
