ID   A0A0S4JFL5_BODSA        Unreviewed;       541 AA.
AC   A0A0S4JFL5;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211};
DE            EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};
GN   ORFNames=BSAL_17210 {ECO:0000313|EMBL:CUG88772.1};
OS   Bodo saltans (Flagellated protozoan).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Eubodonida; Bodonidae; Bodo.
OX   NCBI_TaxID=75058 {ECO:0000313|EMBL:CUG88772.1, ECO:0000313|Proteomes:UP000051952};
RN   [1] {ECO:0000313|Proteomes:UP000051952}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lake Konstanz {ECO:0000313|Proteomes:UP000051952};
RG   Pathogen Informatics;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-
CC         lysyl-[protein]; Xref=Rhea:RHEA:45948, Rhea:RHEA-COMP:9752,
CC         Rhea:RHEA-COMP:10731, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:61930; EC=2.3.1.48;
CC         Evidence={ECO:0000256|RuleBase:RU361211};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU361211}.
CC   -!- SIMILARITY: Belongs to the MYST (SAS/MOZ) family.
CC       {ECO:0000256|RuleBase:RU361211}.
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DR   EMBL; CYKH01001671; CUG88772.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S4JFL5; -.
DR   VEuPathDB; TriTrypDB:BSAL_17210; -.
DR   OMA; AVCEVVY; -.
DR   OrthoDB; 125244at2759; -.
DR   Proteomes; UP000051952; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.40.630.30; -; 1.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR002717; HAT_MYST-type.
DR   PANTHER; PTHR10615; HISTONE ACETYLTRANSFERASE; 1.
DR   PANTHER; PTHR10615:SF161; HISTONE ACETYLTRANSFERASE KAT5; 1.
DR   Pfam; PF01853; MOZ_SAS; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   PROSITE; PS51726; MYST_HAT; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Nucleus {ECO:0000256|RuleBase:RU361211};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051952};
KW   Transferase {ECO:0000313|EMBL:CUG88772.1}.
FT   DOMAIN          151..495
FT                   /note="MYST-type HAT"
FT                   /evidence="ECO:0000259|PROSITE:PS51726"
FT   REGION          117..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  60020 MW;  969FD1799F15853A CRC64;
     MSSGTLAVGT ECILLDHCPE FCVLGIIGDI RQHRDDPSRV LYHFTCVQVD DSCAVEAVTS
     EVEVHGPIVR TWRRPDGKTL VSPDGYPYDF TGWYEESSLE PTEGTEDGTS LAELLESQQR
     AKHSQQVAGG GSSELGSPQE TQMERLLRRA TTDNDPCEIQ YLGLSFRPWF AAPFRSMGYI
     PNTNAADGHV AYSIYLCHRC LGPYADVMSL VSHMELCRVA HPPGFLIYRH VLDVPPSRRQ
     SGPPPEVRAY VIDGAEDVVY CRHLAMLMKS LVESKVIRND VDLYEFVVVT VNRTVAASWC
     APLMGEAGAE ELLRYDPERW DGHVLAGFYC RLKMLPNVGL SCIATMPCFQ KCGVGQLLVR
     LAYYLGFLRQ KYCGCACCGN DGCNIDRPFS VSGNKLLHST WLSVLKKELC ALGSTTDFTF
     DGLRRRCAEE TFMHLSKEDF MDFLLTNHMG FYATGSEGAV GSVVIDQRES ISRVMSHRPA
     FHSLMTFDPT HLIIPSSRTT LVKGGLGVVD AEEALTHFVR LMFHDIADHS DEAGLAVECP
     S
//