ID A0A0S8DB23_9BACT Unreviewed; 655 AA.
AC A0A0S8DB23;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:KPK33014.1};
GN ORFNames=AMK70_09840 {ECO:0000313|EMBL:KPK33014.1};
OS Nitrospira bacterium SG8_35_1.
OC Bacteria; Nitrospirota; Nitrospiria.
OX NCBI_TaxID=1704024 {ECO:0000313|EMBL:KPK33014.1, ECO:0000313|Proteomes:UP000052010};
RN [1] {ECO:0000313|EMBL:KPK33014.1, ECO:0000313|Proteomes:UP000052010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8_35_1 {ECO:0000313|EMBL:KPK33014.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK33014.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LJTK01000157; KPK33014.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8DB23; -.
DR PATRIC; fig|1704024.3.peg.759; -.
DR Proteomes; UP000052010; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.110.200; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 6.20.270.20; LapD/MoxY periplasmic domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR032244; LapD_MoxY_N.
DR InterPro; IPR042461; LapD_MoxY_peri_C.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121:SF23; CYCLIC DI-GMP PHOSPHODIESTERASE PDEB; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF16448; LapD_MoxY_N; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 266..399
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 410..655
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 655 AA; 73825 MW; 8BFBEFB03E2AF947 CRC64;
MTLYRQLVIF TLVLFIILFT GTWLAKLEST RSFLVDQLDS HAQDTATSLG VSISQYSKEN
DLPVIEGMIN AVFDRGYYRI VRYKDSGGNV LIDRVLDVNI ENVPQWFISL VSLKTPEATA
NVMAGWQQAG TIYVKSHPGY AYKTLWENVV RMSIWFLVCG IFVLAAGGVG LRLLLRPLTL
VERQADALCK KQYEIQKQLP RTKELRRVVE AMNRMTTKVR DMFEEQLSIA EGLRKHAYHD
SLTGLGNRRY FESQISARLD RRESKTKGFV LLLQVNNLHE LNQQKGFQAG DELLQRFGAL
LQEATKKDAN AVLARLTGGD FGIFMPDGSS WEAEALAEAV TSQLNQLAVE QLTLTDNVAH
AGAASYESST TMGRLLSEAD LALRSAQQAG PNKWDLRTIT AETDKAPLGQ QQWKDTLDQA
LSERRITLFA QPVVNTYDRN HIIHLEIFSR IIKDDGTLLS AGLFMPFAER LHLVSYIDRI
VLEDVMLLDG DRVGIERVAV NVSPASLQND SFRRWLVFAI ENLPQNAPRI NFEFAEFGAV
QHLEIINEFS SVVRKYGHLV GLDHYGQSFS HLGYLKSLMP DYVKIDRAYT GELKDAASDS
RFFIGSLCSV AHSLDITVIA EGVETEQQWQ LLKELNLDAI QGYIIDRPKP LTEKK
//
