ID   A0A0S8K3Z7_9BACE        Unreviewed;       448 AA.
AC   A0A0S8K3Z7;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Guanine permease {ECO:0000313|EMBL:KPL16600.1};
GN   ORFNames=AMS26_04015 {ECO:0000313|EMBL:KPL16600.1};
OS   Bacteroides sp. SM23_62.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1703352 {ECO:0000313|EMBL:KPL16600.1, ECO:0000313|Proteomes:UP000050819};
RN   [1] {ECO:0000313|EMBL:KPL16600.1, ECO:0000313|Proteomes:UP000050819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SM23_62 {ECO:0000313|EMBL:KPL16600.1};
RX   PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA   Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT   "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT   among widespread estuary sediment bacteria.";
RL   Microbiome 3:14-14(2015).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPL16600.1}.
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DR   EMBL; LJUP01000022; KPL16600.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S8K3Z7; -.
DR   PATRIC; fig|1703352.3.peg.1404; -.
DR   Proteomes; UP000050819; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        21..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        78..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        394..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        430..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   448 AA;  47502 MW;  678DF056AC4F8E91 CRC64;
     MKAWLNRYFR LEENNTNIRT EMVGGITTFM TMSYIIFVQP AILSAAGMDQ GAVMVATCVS
     SAIATLLMGL LARYPIALAP AMGHNVFFAI IVCGIMGYSW QVTLGAVFIS GVILLILSIA
     GVWKTLVAAV PDSLKHSIAV GIGLLIAFVG LQYGGIVVNA PPPVPGTTDI LVVLGDLTSK
     PVLLALFGVV LTAVLMVLKI RGAILLGIFA TSLLGIPLGV IKFQGIVAVP PSLQPTLFKL
     DIPGAFQTGL LTVVFIFFFL DLFDTMGTLI GVSAPAGFLK DGKLPRANQA MFADAVGTVG
     GALLGTSTVT SYIESASGIT HGARTGLANV FTSLLFVIAL FFSPLAAMIA GSVEYSGAIL
     RPVIAPPLII VGFLMMKSIV YIKWDDLAEA IPAYLTILIM PLTFSITEGI AFGFISYSLL
     KLVTGKGRDV HWVIYLFAVL FIIRYIIK
//