ID   A0A0S8KZ13_9PROT        Unreviewed;       255 AA.
AC   A0A0S8KZ13;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:KPL26942.1};
GN   ORFNames=AMJ72_11660 {ECO:0000313|EMBL:KPL26942.1};
OS   Acidithiobacillales bacterium SM1_46.
OC   Bacteria; Pseudomonadota; Acidithiobacillia; Acidithiobacillales.
OX   NCBI_TaxID=1703384 {ECO:0000313|EMBL:KPL26942.1, ECO:0000313|Proteomes:UP000052054};
RN   [1] {ECO:0000313|EMBL:KPL26942.1, ECO:0000313|Proteomes:UP000052054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SM1_46 {ECO:0000313|EMBL:KPL26942.1};
RX   PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA   Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT   "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT   among widespread estuary sediment bacteria.";
RL   Microbiome 3:14-14(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPL26942.1}.
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DR   EMBL; LJVB01000129; KPL26942.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S8KZ13; -.
DR   PATRIC; fig|1703384.3.peg.770; -.
DR   Proteomes; UP000052054; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR   PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          9..70
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51077"
FT   DOMAIN          71..250
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
SQ   SEQUENCE   255 AA;  28081 MW;  491EDA6F4F1B219C CRC64;
     MPKSPESSIQ VIDRAVSLLD ALAAANGPIS LKVLAAESEL HPSTAHRILD ALATHGFVER
     ADNGQYRLGV RLMQYGGRVR EKTDLLREAR PIMDWLREQV GETVNLTVRE GDEVVYVERA
     LPRRMMRVEQ LIGSRAPLHV TAVGKLFLAE VGEAECREYA RRTGLPRYTP NTFTQPGKLW
     IEVGAALKQG YALDNEEAEQ GVACIGVPIR DSHGMMVAGL SVSAPRERRQ DRWISLVKKA
     GADLSARLGY TSKAA
//