ID A0A0T5NS54_9RHOB Unreviewed; 380 AA.
AC A0A0T5NS54;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Nuclease SbcCD subunit D {ECO:0000256|ARBA:ARBA00013365, ECO:0000256|RuleBase:RU363069};
GN Name=sbcD {ECO:0000256|RuleBase:RU363069,
GN ECO:0000313|EMBL:QEW30091.1};
GN ORFNames=RIdsm_05937 {ECO:0000313|EMBL:QEW30091.1}, XM52_28570
GN {ECO:0000313|EMBL:KRS11771.1};
OS Roseovarius indicus.
OG Plasmid pRIdsm_03 {ECO:0000313|EMBL:QEW30091.1}, and
OG Plasmid pridsm_03 {ECO:0000313|Proteomes:UP000325785}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=540747 {ECO:0000313|EMBL:KRS11771.1, ECO:0000313|Proteomes:UP000051401};
RN [1] {ECO:0000313|EMBL:KRS11771.1, ECO:0000313|Proteomes:UP000051401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B108 {ECO:0000313|EMBL:KRS11771.1,
RC ECO:0000313|Proteomes:UP000051401};
RA Li G., Lai Q., Shao Z., Yan P.;
RT "The draft genome sequence of Roseovarius indicus B108T.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QEW30091.1, ECO:0000313|Proteomes:UP000325785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26383 {ECO:0000313|EMBL:QEW30091.1,
RC ECO:0000313|Proteomes:UP000325785};
RC PLASMID=pRIdsm_03 {ECO:0000313|EMBL:QEW30091.1}, and pridsm_03
RC {ECO:0000313|Proteomes:UP000325785};
RA Vollmers J., Petersen J.;
RT "Genetic Globetrotter - A new plasmid hitch-hiking vast phylogenetic and
RT geographic distances.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: SbcCD cleaves DNA hairpin structures. These structures can
CC inhibit DNA replication and are intermediates in certain DNA
CC recombination reactions. The complex acts as a 3'->5' double strand
CC exonuclease that can open hairpins. It also has a 5' single-strand
CC endonuclease activity. {ECO:0000256|RuleBase:RU363069}.
CC -!- SUBUNIT: Heterodimer of SbcC and SbcD. {ECO:0000256|ARBA:ARBA00011322,
CC ECO:0000256|RuleBase:RU363069}.
CC -!- SIMILARITY: Belongs to the SbcD family. {ECO:0000256|ARBA:ARBA00010555,
CC ECO:0000256|RuleBase:RU363069}.
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DR EMBL; LAXI01000050; KRS11771.1; -; Genomic_DNA.
DR EMBL; CP031601; QEW30091.1; -; Genomic_DNA.
DR RefSeq; WP_057821957.1; NZ_LAXI01000050.1.
DR AlphaFoldDB; A0A0T5NS54; -.
DR STRING; 540747.SAMN04488031_11850; -.
DR KEGG; rid:RIdsm_05937; -.
DR PATRIC; fig|540747.5.peg.5153; -.
DR OrthoDB; 9773856at2; -.
DR Proteomes; UP000051401; Unassembled WGS sequence.
DR Proteomes; UP000325785; Plasmid pridsm_03.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00840; MPP_Mre11_N; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041796; Mre11_N.
DR InterPro; IPR004593; SbcD.
DR InterPro; IPR026843; SbcD_C.
DR NCBIfam; TIGR00619; sbcd; 1.
DR PANTHER; PTHR30337; COMPONENT OF ATP-DEPENDENT DSDNA EXONUCLEASE; 1.
DR PANTHER; PTHR30337:SF0; NUCLEASE SBCCD SUBUNIT D; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF12320; SbcD_C; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|RuleBase:RU363069};
KW DNA replication {ECO:0000256|RuleBase:RU363069};
KW Endonuclease {ECO:0000256|RuleBase:RU363069};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|RuleBase:RU363069};
KW Hydrolase {ECO:0000256|RuleBase:RU363069};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|RuleBase:RU363069};
KW Plasmid {ECO:0000313|EMBL:QEW30091.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051401}.
FT DOMAIN 1..218
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 268..352
FT /note="Nuclease SbcCD subunit D C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12320"
SQ SEQUENCE 380 AA; 41092 MW; 213F8EC602DFCADE CRC64;
MRILHTADLH LGRQFNGIPL DSDHAAILDQ IVSAITSRDV DVLVIAGDIF DRAAPPTSAV
RQFNGFLARV ASETDAAVVM IAGNHDSGDR IASMAIMTDT RRALIRGAIS ADEKPLVLTD
AHGPVAFTGL PFAYEYAARE CFSDEALHTP EDVLAAQVAC GRRNIPDGTR WVVVSHAFVA
GASSSESERP LTRVGGIETV SSAVFEGAHY VALGHLHRPQ SVGAPHIRYS GSPLAFGFDE
SDCQKSMSLV EIDAVGQTTI ESIPFTPIRH VRVLKGRHAE LLLADRSDDF IKAVLTDDAP
VIDGMKRIRD VFPNACELIY ERDEQAPEVK SLTGRALAVA NPVEVIGDFV EHVRDEGFSE
KELEVVASAL GRLRETEDVK
//
