ID   A0A0T5ZF13_9ARCH        Unreviewed;       293 AA.
AC   A0A0T5ZF13;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=2-hydroxy-3-oxopropionate reductase {ECO:0000313|EMBL:KRT61408.1};
GN   ORFNames=XU09_C0005G0065 {ECO:0000313|EMBL:KRT61408.1};
OS   Thaumarchaeota archaeon CSP1-1.
OC   Archaea; Nitrososphaerota.
OX   NCBI_TaxID=1640512 {ECO:0000313|EMBL:KRT61408.1, ECO:0000313|Proteomes:UP000051388};
RN   [1] {ECO:0000313|EMBL:KRT61408.1, ECO:0000313|Proteomes:UP000051388}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CSP1-1 {ECO:0000313|EMBL:KRT61408.1};
RA   Hug L.A., Thomas B.C., Sharon I., Brown C.T., Sharma R., Hettich R.L.,
RA   Wilkins M.J., Williams K.H., Singh A., Banfield J.F.;
RT   "Critical biogeochemical functions in the subsurface are associated with
RT   bacteria from new phyla and little studied lineages.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRT61408.1}.
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DR   EMBL; LDXL01000005; KRT61408.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0T5ZF13; -.
DR   STRING; 1640512.XU09_C0005G0065; -.
DR   PATRIC; fig|1640512.3.peg.709; -.
DR   Proteomes; UP000051388; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR029154; HIBADH-like_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          3..160
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          165..284
FT                   /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF14833"
SQ   SEQUENCE   293 AA;  31510 MW;  39B315C8B06856FD CRC64;
     MTRIGVIGTG MLGKAVGLHL LESGYQLTVY NRTKSKTEEL KNHGATVVDS PKDVARSSDL
     VITIVKDANA VKDVSFGKDG IVDGKHDDLI VADMSTINPN ASKEIAKQFS KHGIIMLDTP
     VMGGPNVAIT GKLVLMAAGD KDAFETHKKI FETIASKTFF LGPNGTAHSV KLAMNLQIGM
     LALALSEGIT LARGAGVDPE VFLSILNSTY FKTGMSENKA YNMIKDEYSP TFTLSNLKKD
     LDTINEAAKE FGLKLPMATK ANEIYKKAND EGFGDLDYTG ILAYLKKAAK LVD
//