ID   A0A0T6AFB6_9DELT        Unreviewed;       249 AA.
AC   A0A0T6AFB6;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   13-SEP-2023, entry version 18.
DE   RecName: Full=PurE domain-containing protein {ECO:0000259|SMART:SM01001};
GN   ORFNames=XU12_C0008G0041 {ECO:0000313|EMBL:KRT73574.1};
OS   Deltaproteobacteria bacterium CSP1-8.
OC   Bacteria; Deltaproteobacteria.
OX   NCBI_TaxID=1640514 {ECO:0000313|EMBL:KRT73574.1, ECO:0000313|Proteomes:UP000051991};
RN   [1] {ECO:0000313|EMBL:KRT73574.1, ECO:0000313|Proteomes:UP000051991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CSP1-8 {ECO:0000313|EMBL:KRT73574.1};
RA   Hug L.A., Thomas B.C., Sharon I., Brown C.T., Sharma R., Hettich R.L.,
RA   Wilkins M.J., Williams K.H., Singh A., Banfield J.F.;
RT   "Critical biogeochemical functions in the subsurface are associated with
RT   bacteria from new phyla and little studied lineages.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRT73574.1}.
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DR   EMBL; LDXO01000008; KRT73574.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0T6AFB6; -.
DR   STRING; 1640514.XU12_C0008G0041; -.
DR   PATRIC; fig|1640514.3.peg.1182; -.
DR   Proteomes; UP000051991; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   InterPro; IPR039476; P2CMN_synthase_LarB.
DR   InterPro; IPR000031; PurE_dom.
DR   NCBIfam; NF033503; LarB; 1.
DR   PANTHER; PTHR43064; PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE-RELATED; 1.
DR   PANTHER; PTHR43064:SF1; SLL1489 PROTEIN; 1.
DR   Pfam; PF00731; AIRC; 1.
DR   SMART; SM01001; AIRC; 1.
DR   SUPFAM; SSF52255; N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE); 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        171..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          120..249
FT                   /note="PurE"
FT                   /evidence="ECO:0000259|SMART:SM01001"
SQ   SEQUENCE   249 AA;  26247 MW;  5E8C658BFAB26681 CRC64;
     MTAKMLKQLL RQVAEGKASV DTAFRKIRSL PFENIGMASV DHHRAIRQGV PEVILGEGKT
     PAQIVRIARA MRKAGADVLI TRVDEEKRKA VRKHFRRASL YPEARCAVIR SAAAEKDGKG
     NILVVTAGTS DIPVAEEAAV TAEFLGNRVE RLYDVGVAGI HRLLMQKEAL LSARVIVVVA
     GMEGALASVV GGLTDKPVIA VPTSVGYGAS FGGVAALLGM LNSCSPTVAV VNIDNGFGAG
     VLSSVINRL
//