ID A0A0T6B2Y4_9SCAR Unreviewed; 874 AA.
AC A0A0T6B2Y4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE SubName: Full=SH3 domain-containing protein {ECO:0000313|EMBL:KRT81807.1};
DE Flags: Fragment;
GN ORFNames=AMK59_6036 {ECO:0000313|EMBL:KRT81807.1};
OS Oryctes borbonicus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Scarabaeiformia;
OC Scarabaeidae; Dynastinae; Oryctes.
OX NCBI_TaxID=1629725 {ECO:0000313|EMBL:KRT81807.1, ECO:0000313|Proteomes:UP000051574};
RN [1] {ECO:0000313|EMBL:KRT81807.1, ECO:0000313|Proteomes:UP000051574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OB123 {ECO:0000313|EMBL:KRT81807.1};
RC TISSUE=Whole animal {ECO:0000313|EMBL:KRT81807.1};
RA Meyer J.M., Markov G.V., Baskaran P., Herrmann M., Sommer R.J.,
RA Roedelsperger C.;
RT "Draft genome of the scarab beetle Oryctes borbonicus.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRT81807.1}.
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DR EMBL; LJIG01016036; KRT81807.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0T6B2Y4; -.
DR OrthoDB; 2904755at2759; -.
DR Proteomes; UP000051574; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07656; F-BAR_srGAP; 1.
DR CDD; cd04383; RhoGAP_srGAP; 1.
DR CDD; cd11809; SH3_srGAP; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14166:SF17; RHO-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14166; SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000051574};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 20..301
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 484..672
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 716..775
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 690..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 837..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 163..197
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 690..707
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 874
FT /evidence="ECO:0000313|EMBL:KRT81807.1"
SQ SEQUENCE 874 AA; 101412 MW; F41AAA67EFDF0186 CRC64;
MMKSYKWHKK LNVDFLDETE DIRLQLNEQL RCLDMRMEAQ VALVTELQDF FRRRGELELD
YSKNLDKLAK SLQIRHKEQK QKREQWPLFS SYACWQQLVT QTRNLSRDHV ALSEVYSTHL
VSRLAQVMED VQRIYKKCRD IGYETHEEIL RVLHELHTTM KTYHSYQGEL RQADEKLKSA
ENQRNKLKQT LTQDKLERSK KYKFMEKEVM KRKSKYTDAK LKALKARNEY ILCLEASNTT
IHKYFVDDLS DLIDCMDFGF HNCISRALLM HVSAEEGRQR SVQHGMDTLS ACINSLDSGT
DKQKFLEYNH SAFMIPKKIE FQGQKTDDQT PEPEIQKILH QEMETRLNHL HMRVTNLRAE
SDEVWKTLET AERTLLEMLN AKDYDCSQYF GETAIPATKP PESLSMKQRA DRQETEEFYL
SKFREYLLGS TRIARLDAKQ KYITQSLLSE TPEAVNTLKP ISKTPRRKRI GRLQLSGQPK
LFGGSLEEYL EATNQEIPLI IKSCVRVINL YGLHHQGIFR VSGSQVEINN FRDAFEKGED
PLSEMTDSSD INSVAGVLKL YLRELREPLF PIIYFEQFME LAQLESKREF ITKIKELVLS
LPRPVMVVMR YLFAFLNHLS EFSDENMMDP YNLAICFGPT LVPVPDDKDQ VQYQNQVNEL
IKNIIMYNDE IFPNDGGCIY EKYISLEPDD HDVGDSPSDH AQEDLDSEVY PSEDDSECME
ATAQFDFIAR SDRELSLRKG DTVTLYSQVS NDWWKGAVNG NEGLIPDKYI SLKMKDDDRE
KIENFKSSSS DDSMRRRASS SNDSVLSESS ISAANSPLVQ CAPITWSNVP NLNEDVPTNS
STIMTQSRES LSGSHKRNKS MDMSTEFRSN LNPN
//
