ID A0A0T6UNH2_9PSED Unreviewed; 315 AA.
AC A0A0T6UNH2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Dihydrodipicolinate synthetase {ECO:0000313|EMBL:KRW59503.1};
GN ORFNames=AO726_11865 {ECO:0000313|EMBL:KRW59503.1};
OS Pseudomonas sp. TTU2014-080ASC.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1729724 {ECO:0000313|EMBL:KRW59503.1, ECO:0000313|Proteomes:UP000051864};
RN [1] {ECO:0000313|EMBL:KRW59503.1, ECO:0000313|Proteomes:UP000051864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTU2014-080ASC {ECO:0000313|EMBL:KRW59503.1,
RC ECO:0000313|Proteomes:UP000051864};
RA Webb H.E., Bugarel M., Den Bakker H.C., Nightingale K., Granier S.A.,
RA Loneragan G.H.;
RT "Carbapenem-non-susceptible Bacteria Recovered from the Faeces of Dairy
RT Cattle.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRW59503.1}.
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DR EMBL; LKKK01000011; KRW59503.1; -; Genomic_DNA.
DR RefSeq; WP_058068304.1; NZ_LKKK01000011.1.
DR AlphaFoldDB; A0A0T6UNH2; -.
DR STRING; 1729724.AO726_11865; -.
DR OrthoDB; 6142028at2; -.
DR Proteomes; UP000051864; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000051864}.
FT ACT_SITE 136
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 164
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 209
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 315 AA; 34255 MW; 7A018392D0FAA294 CRC64;
MSDNIFTGCI PALMTPCTAD RQPDFDALVA KGKELIELGM SAVVYCGSMG DWPLLSEAQR
QEGVARLVAA GVPTIVGTGA VNSKEAVSHA AHAAKVGAQG LMVIPRLLSR AVSPAAQKNH
FKAILQAAPK LPAVIYNSPH YGFSTRADLF FELRSAHPNL IGFKEFGGAE PLRYAAEHIT
STNDDITLMV GVDTQVVHGF VNCNATGSIT GIGNVLPREV LQLVELSKKA AKGDPKARRQ
AQELENALAV LSSFDEGTDL VLYYKYLMVL NGDQEYTLHF NETDVLSDAQ RNYAENQYAL
FRQWYSSWMA EQNFA
//
