ID A0A0U1NJ10_9RHOB Unreviewed; 1011 AA.
AC A0A0U1NJ10;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:CRK74695.1};
DE EC=2.1.2.10 {ECO:0000313|EMBL:CRK74695.1};
GN Name=gcvT_3 {ECO:0000313|EMBL:CRK74695.1};
GN ORFNames=NIG5292_00730 {ECO:0000313|EMBL:CRK74695.1};
OS Nereida ignava.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Nereida.
OX NCBI_TaxID=282199 {ECO:0000313|EMBL:CRK74695.1, ECO:0000313|Proteomes:UP000048949};
RN [1] {ECO:0000313|EMBL:CRK74695.1, ECO:0000313|Proteomes:UP000048949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5292 {ECO:0000313|EMBL:CRK74695.1,
RC ECO:0000313|Proteomes:UP000048949};
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CVQV01000003; CRK74695.1; -; Genomic_DNA.
DR RefSeq; WP_048598066.1; NZ_CVQV01000003.1.
DR AlphaFoldDB; A0A0U1NJ10; -.
DR STRING; 282199.GCA_001049735_00730; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000048949; Unassembled WGS sequence.
DR GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:CRK74695.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000048949};
KW Transferase {ECO:0000313|EMBL:CRK74695.1}.
FT DOMAIN 172..429
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 530..612
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 627..892
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 918..1003
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 1011 AA; 109808 MW; ADED91DF582B49B2 CRC64;
MSTRLANGGR LIDRNAKVDF TLNGKRLSGF AGDTLASALL GEDQMLMGRS FKYHRPRGVV
ASGAEEPNAL MNLGEGNTFE PNARATTTPL FGGLKAASQN HWPSLEFDVG AINKHLSRFL
PAGFYYKMFI HPRPLWKHVY EPFIRRSAGL GRAPEAEARD PDTYEHFYHH TDVLIIGGGT
AGLSAALTAG RAGLDVTLME QNAEWGGRAP VDATCGGPSE IDGVSVDEWI NNAIQALEKM
KNVTLRTRTM GAGVYDHGYV LCYERLRDHA PELDGPRHRL WKVRAQQIIT ATGAIERPLS
FAGNDIPGVM LASAVRDYAV NYGVSAGDRT VVVTNNDDAY RTAIAMVQAG LSVPAIVDAR
TMADQGLVSQ ARALGIEVKQ GMGIAKVKGT KRVTGVALCL QAGEGAVLEE IKCDVVAMSG
GWSPVVHMWS HCGGKLTWDE DGQFFRPDPD RAPTSHDGKA FVSVAGAANG HMMLGAGLAD
GASCAAKVVA ACGKKVKAKD PVPSATDVTE APMAPVWIMP QGANISLRAK MWLDYQNDVK
VSDVQLAAQE GYESVEHTKR YTTLGMATDQ GKLSNINGLA VLSGALNAPI PAVGTTTFRP
PYTPISMGSI AGEAKGDIFQ PMRRSPLHDW HDDNGVYWEP VGHWRRPYCY TRDGESHADA
VNREVKNTRE NLGLLDASTL GKIIVKGPDA GRFLDMLYTN MMSNLKVGRC RYGLMCSENG
FLMDDGVVAR IDEDTWLCHT TSGGADHIHQ HMEEWLQTEW WDLKVYVANV TEQYGQIAVV
GPNARKVLET LGGMDVSQDA LSFMGWADGT LAGIDVRIFR ISFSGELSYE IAVKAGQARA
LWDAIYKAGQ GFGVMPYGTE TLHVLRAEKG FIMIGDETDG TVIPQDLNLQ WALSKKKEDY
LGKRAHERSF MADPARWKLV GLLTTDRSVI PDGAYAVADG VNDNGQRNTQ GRITSSYYSA
TMERGIAMAL VKDGPDRMGE VLTFPKTDGT EVRAEIVDPV FYDKEGAKQN V
//
