ID A0A0U2W6W1_9BACL Unreviewed; 601 AA.
AC A0A0U2W6W1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:ALS23149.1};
GN ORFNames=IJ22_27760 {ECO:0000313|EMBL:ALS23149.1}, PN4B1_16230
GN {ECO:0000313|EMBL:GCL71718.1};
OS Paenibacillus naphthalenovorans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=162209 {ECO:0000313|EMBL:ALS23149.1, ECO:0000313|Proteomes:UP000061660};
RN [1] {ECO:0000313|Proteomes:UP000061660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=32O-Y {ECO:0000313|Proteomes:UP000061660};
RA Butler R.III., Wang J., Stark B.C., Pombert J.-F.;
RT "Complete genome sequences of two moderately thermophilic Paenibacillus
RT species.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ALS23149.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=32O-Y {ECO:0000313|EMBL:ALS23149.1};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ALS23149.1, ECO:0000313|Proteomes:UP000061660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=32O-Y {ECO:0000313|EMBL:ALS23149.1,
RC ECO:0000313|Proteomes:UP000061660};
RX PubMed=26868401;
RA Butler R.R.III., Wang J., Stark B.C., Pombert J.F.;
RT "Complete Genome Sequences of Two Interactive Moderate Thermophiles,
RT Paenibacillus napthalenovorans 32O-Y and Paenibacillus sp. 32O-W.";
RL Genome Announc. 4:e01717-15(2016).
RN [4] {ECO:0000313|EMBL:GCL71718.1, ECO:0000313|Proteomes:UP000299945}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4B1 {ECO:0000313|EMBL:GCL71718.1,
RC ECO:0000313|Proteomes:UP000299945};
RA Ha-Thanh L.T., Ngoc-Thi T.V., Shintani M., Moriuchi R., Dohra H.,
RA Hoang-Loc N., Kimbara K.;
RT "Isolation and characterization of a moderate thermophilic Paenibacillus
RT naphthalenovorans strain 4B1 capable of degrading dibenzofuran from dioxin-
RT contaminated soil in Vietnam.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP013652; ALS23149.1; -; Genomic_DNA.
DR EMBL; BJCS01000004; GCL71718.1; -; Genomic_DNA.
DR RefSeq; WP_062409192.1; NZ_CP013652.1.
DR AlphaFoldDB; A0A0U2W6W1; -.
DR STRING; 162209.IJ22_27760; -.
DR KEGG; pnp:IJ22_27760; -.
DR PATRIC; fig|162209.4.peg.2956; -.
DR OrthoDB; 2985542at2; -.
DR Proteomes; UP000061660; Chromosome.
DR Proteomes; UP000299945; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000061660};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..220
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 279..596
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 601 AA; 66047 MW; 24BFFBE3AFFAFB5D CRC64;
MNDETELKKH RMFLALLLIV GLLAVWNIRL FWIQVVATRS FTGRGIDLLA NSVIQRENGI
VLDSGRGDFV DRNGDPLTGK ELKVLTVFPV REEGSAGGRR EESLNRIAEW MGIPGKEWHI
FVRGLKSPEI WSESGRPVAL TDSQAERIEA LGLPDVRVMR YKQRYAQQQP ASHVIGFIGQ
NPERIMEQFS GQIQKGELQL TSKIGNAGLE KTFDYWLQGI GATSVSLFTD GMKRPLPGLD
VRMISPDNPY YPLKMVTTLN KGIQSHIEFQ MERLGIAEGA VVVLDIRNAD TVAMASRPSF
HPGHVDPTEG HWSNRALKAT VPGSIFKTVT AAAALEEKAV HPDETFECNG ELGKYGFTCW
KKGGHGHLTL EEGFAQSCNI VFAEAAKRIG AEKLEQYAQK LGLGTLVGWS GAVPGQADFR
QWDGEEKGQV YHLSTDKRDE GALVQTAIGQ RDVQVTPLQV ANLVVSLYAQ GKVLSPRIVQ
EIRFQNDRLH TSFPPRGLAP EGAAPISPDT AQRLLAWMKE VVDHGTGTAL QAAKWPLAGK
SGTAQLTLKN GKPGENHWFI GYGPADQPRY AVAVLVQNVP QGYGNKSVPL FKEVMDILAA
P
//
