ID A0A0U3P0D0_9ACTN Unreviewed; 550 AA.
AC A0A0U3P0D0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=AS200_27690 {ECO:0000313|EMBL:ALV35408.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV35408.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV35408.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV35408.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; CP013743; ALV35408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U3P0D0; -.
DR STRING; 1725411.AS200_27690; -.
DR KEGG; scx:AS200_27690; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT DOMAIN 6..137
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 140..493
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..550
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 324
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 550 AA; 60619 MW; 48BFF210D93410A4 CRC64;
MTVRTGLIPA PAEFSPPGDG AGHLLDAGSG IDAGPGTERV AQWLRATVGA ATGLPLPPHT
GGRDGIVLRL DPRESDDPEG YGLTVDRHAI TLRAAAEPGL FHAAQTLRQL LGPDAFRRAP
VTSGRPWEVP AVAVRDAPRF RWRGLMLDVA RHFMPKDGVL RYLDLMAAHK LNVLHLHLTD
DQGWRVEILK HPRLTEVGAW RARTRFGHRA SPLWERKPHG GFYTQDDIRE IVAYAAERHV
TVVPEIDVPG HSQAAIAAYP ELGNTDVVDT TALSVWDDWG ISPHVLAPTD TTLRFYEDVF
EELLGLFPAD AARFSRFVHI GGDECLKDQW AASPTAQARI RDLGLDGEDG LQAWFVGHFD
TWLTARGRRL IGWDEILEGG LAKGAAVSSW RGCAGGVAAA RAGHDVVMCP EQYVYLDHRQ
DAGAQEPVPI GYVRTLEDVY RFEPVPPELT PEEAAHVLGA QANVWTEVME DHARVDYQAF
PRLAAFAEVA WSRLPAPEQR DFAGFEERMA EHYRRLDALG VGYRPPSGPR PWQRRPGVPG
RPIEGAPPNR
//
