ID A0A0U3PTS4_9ACTN Unreviewed; 3179 AA.
AC A0A0U3PTS4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=AS200_00905 {ECO:0000313|EMBL:ALV30812.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV30812.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV30812.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV30812.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP013743; ALV30812.1; -; Genomic_DNA.
DR STRING; 1725411.AS200_00905; -.
DR KEGG; scx:AS200_00905; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd12117; A_NRPS_Srf_like; 3.
DR CDD; cd19540; LCL_NRPS-like; 3.
DR Gene3D; 3.30.300.30; -; 3.
DR Gene3D; 3.40.50.980; -; 6.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 3.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 3.
DR Pfam; PF13193; AMP-binding_C; 3.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 3.
DR SMART; SM00823; PKS_PP; 3.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR PROSITE; PS00455; AMP_BINDING; 3.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT DOMAIN 975..1050
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2024..2099
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3073..3148
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 3179 AA; 340308 MW; A17A0E9D272C0142 CRC64;
MIPLSYAQQR LWFLAQLEGP SATYNIPLAL RLSGDLDTEA LTWALADVVA RHESLRTLYP
EREGTPYQHI LPAEDARPAL PVLTAGEDTL ADVLAAESAH VFDLAADLPV HARLIRLGDR
EHVLLVVMHH IASDGWSIAP LLRDLAHAYA ARRDGHAPEQ QPLEIQYADF TLWQQEVLGE
PDAEDSLMNR QLAYWKKQLA DLPEEVTLPA DRPRPAVASY RGDTVTVHCP AGTHAALADL
ARESGATLFM AAQAALATVL AAGGAGPDIP LGSPVAGRTE EALNDLVGFF VNTLVLRTDV
TGDPTFRELL NRVRSTDLAA WAHQDVPFDR LVEILNPERS GARHPLFQVM LTLVQAGSTD
PGADFRGLRA RAEYSATRTA KFDLTVGFDE HLTPDGRPAG LDITAEYATD LYDRDTIEAL
LARLLRLLGE ASARPDTPLS GLDLLDAAER TLLLDTWTGR ATPVPEASLA ALFAEQAART
PDAVALTHAG RSWTYAEADA VSSRFAHRLT ALGVGPESVV AVLMERSADL VLALLAIVKA
GGVYAPLNAV DPVSRLTRIL ADTAAPLLLT DPHLADHEIV AEAGTTGTRI LRVDDLTADP
ENAPYPASAP KVATHPDQWL YVMFTSGSTG VPKGVAITHR NVAELALDHR WDRPAHRRVL
FHSPHTFDAS TFELWVPWLT GGTVAVAPAG VLDTAALAAV LAEESITGLW LTAGLFRLVA
EEDPAAFAGL GEVWTGGDVV PPEAVRRVMD ACPDLQVVNG YGPTETTTFA TSHFLHRPFD
YAGALPIGRP LDNTRLYVLD EHLGLVAPGV PGELYIAGAG LARGYLRRPA QSAERFVADP
HGPAGARMYR TGDLVRWSRD GEIEYLGRAD QQVKLRGFRI EPGEIESALV AHASVSQAAV
VVREDRPGDK RLVAYVVGDG VDLDALRSHA SQVLPDYMVP AAFMTLNALP LTGNGKLDRR
ALPAPDLSAD STGRAPRNPA EEVLCGLFAD VLGRPSVTID DHFLRLGGHS LLATRLVSRI
RTAFGVRITV RDMFQHPTVA QLAELIRTSN GDQPRPALTA AERPARLPLS SAQQRLWFLD
QLEGPSATYN IPLALRLTGP LDTDALRLAL TDVVGRHEAL RTVFRTADGE AYQLVLPADG
ITVPLPVTPA DEDSLPALLA EESARTFDLA AALPLRASLL RLTDEDHVLV VVTHHIASDG
WSNAPFFTDL HHAYAARTEG AAPEWAPLPV QYADYTLWQH QLLANEQSPQ LAFWRAALAD
LPEEATLPTD RPRPAVASYQ GATLTVSCPA ATHAALTGLA RESGTTLFMV AQAAVATVLS
RCGGGVDVPI GSPVAGRTDE ALDDLVGFFV NTLVLRTDVG GDPTFRELLA RVRETDLAAW
AHQDLPFDRL VEVLNPERSA SRHPLFQVML TVGDTTVSEP ELGSLTARFI TPETRVAKFD
LTFAFGERRA ADGSPDGLDI TVEYATDLYD TTTAASIAGR LARLLDAAVS TPDQPVSTLP
LLTDDDHSRL THWSGPLTRA PQLGLDGLFS GQAARSPEAV ALVFEDQQVT YGELEVWSNR
LARYLSGKGV RPGDLVGVHV ERSPHMVAAI LAVLKTGAGY TMLDPQFPQE RLNGVLEQVR
PSALVTQSHL PPLRTDAVRI DLTGEVADIS ATSGAAVETG GCPESVACVM FTSGSTGVPK
GVAASHRALA ATFVGPDYLA FGPQQTFLQC SPVSWDAFAL EVFGPLLHGG VCVLQPGQHT
DPHQIVELVE RHQVTTLQMS ASLFNHMLDE HPAVFGQLRE AMTAGEAASP AHVARALEAH
PHLRLLNGYG PAESMGFTTT YTIEPGTAEG VASIPVGGPL AGKHTYVLDA NLELVAPGVP
GELYVAGHGL AHGYIGQPGL SADRFVANPH GPAGSRMYRT GDLARWNEQG ALEYLGRGDQ
QIKLRGFRIE PGEVEAALTS HPLVQQAACV VREDRPGDKR LVAYVVGDTA DSAALLRHTA
ARLPEYMVPA AVVVLDELPR TVNGKLDRRA LPAPDLSAAS EGRAPRNPAE EILCGLFADT
LGLASVTIDD HFFHRGGHSL LATRLTSKIR QAFGVRLGVR EIFQYPTAGR LAELIAAGTG
ADERPALLAG ERPARPPLSS AQQRLWFLDQ LEGPSPTYNI PLTVRLTGTL DAEALRRALL
DVVGRHEALR TTFPSENGTP HQAVRSLAET DLALPVTPVT EESLHQTLAR LAGVTFDLAA
DLPIRADLLA LSPEEHVLLV VMHHIASDGW SNGPLLRDLA TAYTARSQGV APEWVPLPVQ
YADYSLWQRR LLTTEEERQL AFWQAELAEL PQEATLPADR PRPAVASYRG ATHKVTAPAA
THAALTGLAR ESGTTLFMVA QAAVATVLSR CGGGVDVPIG SPVAGRTDEA LDDLVGFFVN
TLVLRTDVGG DPTFRELLAR VRETDLAAWA HQDLPFDRLV EVLNPERSAS RHPLFQVMLT
VGDTTAGTPD LAGLETAFLD PELNIAKFDL TFAFGERRAA DGSPDGLDIT VEYATDLYEP
RTVGLLLERT LLLLESAAAA PDTPVGSLPL LTPEEQTLLD TWSGPATAAP RLGLDGLFSA
QAARSPEAVA LVFEDQQVTY GELEVWSNRL ARYLSGKGVR PGDLVGVHVE RSPHMVAAIL
AVLKTGAGYT MLDPQFPQER LNGVLEQVHP AALVTQSHLP PLRTGAVRVD LTAETAEISA
VPGGPVETGG CPESVACVMF TSGSTGLPKG VAASHRALAA TFVGPDYLAF GPQQTFLQCS
PVSWDAFALE VFGPLLHGGV CVLQPGQHTD PHQIVELVER HQVTTLQMSA SLFNHMLDEH
PAVFGQLREA MTAGEAASPS HTAQALARFP HLRLLNGYGP AESMGFTTTY TIEPGTAEGV
ASIPVGGPLS GKHTYVLDAN LELVAPGVPG ELYVAGHGLA HGYIGQPGLS ADRFVANPHG
PAGSRMYRTG DLARWSRDGE IEYLGRADQQ VKLRGFRIEP GEIESALVAH PSLSQAAVVV
REDRPGDKRL VAYVVGDTAD SAALLRHTAA RLPEYMVPAA VVVLDELPRT VNGKLDRRAL
PAPDLSAACE GRAPRNPAEE ILCGLFADTL GLASVTIDDH FFHRGGHSLL ATRLISRIRT
VWDTRVTIRD LFQSPTPALL AEHIAAGSGG NPLDTVLPIR AAGRDTQAAP CSACTPSPG
//
