ID A0A0U3QFE6_9ACTN Unreviewed; 739 AA.
AC A0A0U3QFE6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=AS200_26505 {ECO:0000313|EMBL:ALV35204.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV35204.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV35204.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV35204.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP013743; ALV35204.1; -; Genomic_DNA.
DR RefSeq; WP_058924820.1; NZ_CP013743.1.
DR AlphaFoldDB; A0A0U3QFE6; -.
DR STRING; 1725411.AS200_26505; -.
DR KEGG; scx:AS200_26505; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..739
FT /note="SSD domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039387010"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 663..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..329
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 717..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 739 AA; 76554 MW; 39B881F0838A4BEE CRC64;
MATFLYRLGR FAFRRRHFVA LFWVALLTLA GVAAAGAPAA GSTSFSIPGT EAQKAFDLLD
QRFPGSSSGG ATARVVFKAP GGEKMTDAAH KATVEKTVKE LSDGSEVTSV ADPYTAHAVS
KDGTVAYASV RYDKPGMELK DASRTALKDT ARQARDAGLT VEIGGDALQA GAEPGAAGEV
VGLAIAAVVL VVTLGSLVAA GLPLLTAIIG VGIGVSTITV LAKALDLGDT TSTLALMIGL
AVGIDYALFI VSRYRGELAE GREREEAVGR AAGTAGSAVV FAGLTVMIAL AGLSVVGVPM
LTKMGLAAAG TVLVAVLIAL TMIPALLGYA GRKVRPAGEK RRKPDAARST RPGLGERWAS
FVVRRPAAVL LLGAVGLGAV AVPATQLELG LPDDGSQPTS TTQRRAYDLL SDGFGPGFNG
PLMIVVDAKG SDDPKAAATR VGDDIKGLKD VATVTPAMFN KAGDTAMITV VPGSKPSSAQ
TEDLVHAIRG KGADVRADTG AKVLVTGTTA MNIDFSQKLN DALIPYLGLV VGLAFLLLIA
VFRSILVPLK AALGFLLSVL AALGAVVAVF QWGWLGGLLG VEQTGPIMSM MPIFMVGVVF
GLAMDYEVFL VTRMREAYVH GETPGQAVVT GFRHSARVVA AAAVIMIAVF GGFITSSESM
IKMIGFGLAI AVFFDAFVVR MAIVPAVLAL LGRRAWWLPK WLDRALPDVD VEGEGLKTLD
TADGDRDSDP DEDRKLVRA
//
