ID A0A0U3QKL6_9ACTN Unreviewed; 644 AA.
AC A0A0U3QKL6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Copper resistance protein CopC {ECO:0008006|Google:ProtNLM};
GN ORFNames=AS200_14130 {ECO:0000313|EMBL:ALV33065.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV33065.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV33065.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV33065.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP013743; ALV33065.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U3QKL6; -.
DR STRING; 1725411.AS200_14130; -.
DR KEGG; scx:AS200_14130; -.
DR OrthoDB; 4270482at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR GO; GO:0046688; P:response to copper ion; IEA:InterPro.
DR Gene3D; 2.60.40.1220; -; 1.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR007348; CopC_dom.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF04234; CopC; 1.
DR Pfam; PF05425; CopD; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..644
FT /note="Copper resistance protein CopC"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006843767"
FT TRANSMEM 150..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..127
FT /note="CopC"
FT /evidence="ECO:0000259|Pfam:PF04234"
FT DOMAIN 311..397
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
SQ SEQUENCE 644 AA; 67268 MW; 97AEC9C648988139 CRC64;
MTCCAPTVRR SAVAIGSFVL LVLALLLGTA APASAHATLL FTGPAADATV ADSPKSLVLV
FDQPVSLRGT SVRLEPSAGL GTAMLSRGNQ AVTIPVRTTL AEGVHTVDWQ ITARDGDVMT
GSYRFAVGPR TVALASGQTT AAKDATPTTV LRWLLFAALA VVLGEWAGRR LTARVSDTPA
RRPRSWALPG AFVGTASALA LAGLQIGDGS LASLTGSRPG VLSLIEIVGF GLAAVAILVR
RQVWARLPLA AVLIAEALRA HPEAEQAVAG PLLTFVHLTA AALWAGTLLH VLRTLVAWRS
GQSPVRGLLL SYARLAAWLF AAVVVTGLIS ALLLVPLDNL TTTTYGQVLL VKIALVAVVA
AFALAARRRL RRGGTGSPQC PARAENGVLV VVLVFSATLT VLSVPADANR ALPFAPPLDG
PVVPAGTRAG EIGISARAVA SQLVIDLTAP QISGGEKESY GLKATLADPG GTRRALKLRG
CGTGCFYAPV TWRTGTSRLT LSASAGKEWA GGRAGLAVTW PPRPDPSLLR QTVSAMKQVP
RLTLHELVTS NTARGLGDLR QLPLTGKDFL ASEPYGSSTA PVLTRLPDES GHRRLALAYP
AEHTQLDLTL DETGRILRET LTAPNHLVTR TFVYPEANED GHDH
//
