ID A0A0U3R622_9MICC Unreviewed; 562 AA.
AC A0A0U3R622;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:ALV47477.1};
GN ORFNames=MB46_06730 {ECO:0000313|EMBL:ALV47477.1};
OS Arthrobacter alpinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=656366 {ECO:0000313|EMBL:ALV47477.1, ECO:0000313|Proteomes:UP000055883};
RN [1] {ECO:0000313|EMBL:ALV47477.1, ECO:0000313|Proteomes:UP000055883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A3 {ECO:0000313|EMBL:ALV47477.1,
RC ECO:0000313|Proteomes:UP000055883};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP013745; ALV47477.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U3R622; -.
DR STRING; 656366.AS189_12935; -.
DR KEGG; arw:MB46_06730; -.
DR eggNOG; COG3850; Bacteria.
DR Proteomes; UP000055883; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF56; OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DOST; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ALV47477.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 46..193
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 470..560
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 562 AA; 60340 MW; D2A583E15F1DD2C7 CRC64;
MLPAAAGTRI EDLLREFVDR AGELLSTQER MRGLLAAVVS VAEDLSLDAV LERVVKSACT
LLDARYAALG VIGENQSLSH FITVGIDQEL ITEIGPLPTG HGVLGLLTSD PHPLRLHDLH
DHPASYGFPE HHPPMVSFLG VPVRVRGKVF GNLYLTEKAG GEDFTAEDEE LAVALAAAAG
VAIENARLFE DARRRSRWLE ACMDVTGKMM DDERNITESS LDMIAATALA ESDSSLTMIG
VSSDRGPELY VAAAAGERAP LLAGRSLALD SPEIAEVLRT GVPTVFEDAT DLLGTEDGIS
FGPIIVIALG PQGPNQGLLI LARSQGSGSY SKIVVEMSAV FGSHVALALE LARTHRLREQ
IMVFTDRDRI AKDLHDVVIQ RLFAAGLSIQ SLQRFITDKT ASERIRAVTT ELDETIRDLR
NTIYSLRVSS GETELLSDLI LRTVRNAAKT LAFAPRLNLA GPIDSAVSEE TAKHLLAVLS
EGLSNAVRHS DAGAIEVSVD VTSELVRVII DDDGIGVGDL DHRSGLLNME QRAEILHGTF
DLESGENSGT RLTWSVPAAD AH
//
