ID   A0A0U4B0S7_9BACT        Unreviewed;       798 AA.
AC   A0A0U4B0S7;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=AUC43_17150 {ECO:0000313|EMBL:ALW86653.1};
OS   Hymenobacter sedentarius.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Hymenobacter.
OX   NCBI_TaxID=1411621 {ECO:0000313|EMBL:ALW86653.1, ECO:0000313|Proteomes:UP000059542};
RN   [1] {ECO:0000313|EMBL:ALW86653.1, ECO:0000313|Proteomes:UP000059542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG5B {ECO:0000313|EMBL:ALW86653.1,
RC   ECO:0000313|Proteomes:UP000059542};
RA   Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; CP013909; ALW86653.1; -; Genomic_DNA.
DR   RefSeq; WP_068196486.1; NZ_CP013909.1.
DR   AlphaFoldDB; A0A0U4B0S7; -.
DR   STRING; 1411621.AUC43_17150; -.
DR   KEGG; hyg:AUC43_17150; -.
DR   OrthoDB; 5401121at2; -.
DR   Proteomes; UP000059542; Chromosome.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   CDD; cd00130; PAS; 3.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 2.10.70.100; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 4.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF37; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00091; PAS; 4.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50112; PAS; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059542}.
FT   DOMAIN          80..150
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          205..277
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          448..496
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          689..779
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   COILED          42..71
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   798 AA;  87764 MW;  6D9352038CB94418 CRC64;
     MPKLPDPTLA TQAQQRLRNW AAQPRVEELT AKLKDAGTSP EVQRLVQELQ VHQIELEMQN
     EELLAAQAAA ETARLAAEAS RAQYAELYDF APAALFSLRP DGRIAQLNDR ACRLLGTTAA
     RLTDRRFLLF VSPKSRDDFR AFFDNVLQNR QRHTAELHLQ TSAGADFVAH LEGTAATSAA
     GGPIAQLAVV DVTALSQAVE RRQRSDEQLQ LALAASGTGV WVWTLATNLL EWDARAQRCF
     GRPHDPAPTS FSVLQSAVHP DDVVAVQRAL QATVQHGHPL DLQLRVNWPD ATVHYLSAHG
     KVQYDAQGKP ESLVGLVRDE TGRCAVEEEL DYRNRQVQQL LDNLPMLFAR LSPAGEYLEV
     AGAGLRRIGV ESKDLVGQSV FKTSPTLSEP LRRLLAGEPV NFVGNVEVKG EQLYFQNYGF
     FDQQRRQAVL FAIDVTESEQ MKKQLLEEQQ FTKSLLNHSL DGVAAFDPAG RLTAWNRAME
     ALTGRAEADA IGQDVFACLP FDRSSAPGRI VDHLLHGAHR PHFHQPFKQT APDRDFELTA
     ISLNPDGGGL LMLHDVTERN RLHAAAANFR SQQQRETFRM VLLAQEIERK RISEALHNGV
     GQLLYATKLH LEESADAPSA TGAALALLEE AIKATRSVSF ELTPSILEDF GLAVALQKLC
     KNIPPDKLRL HLYLSGLEQP LPLVLTVAIY RMVQELLSNV MKHARAEEAT LHVVHENHQV
     NISMEDNGSG FDVATTVGMG KGIGLTSLYN RAALLGGQFE LVSRRGRGTI ATITLPVVEE
     MPEPTVSEAA GEAPTPAE
//