ID A0A0U5AHI0_9EURY Unreviewed; 384 AA.
AC A0A0U5AHI0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Ion channel pore / TrkA domain protein {ECO:0000313|EMBL:CQH60385.1};
GN Name=pchA3 {ECO:0000313|EMBL:CQH60385.1};
GN ORFNames=HHUB_3199 {ECO:0000313|EMBL:CQH60385.1};
OS Halobacterium hubeiense.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=1407499 {ECO:0000313|EMBL:CQH60385.1, ECO:0000313|Proteomes:UP000066737};
RN [1] {ECO:0000313|Proteomes:UP000066737}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JI20-1 {ECO:0000313|Proteomes:UP000066737};
RX PubMed=26628271; DOI=10.1111/1462-2920.13130;
RA Jaakkola S.T., Pfeiffer F., Ravantti J.J., Guo Q., Liu Y., Chen X., Ma H.,
RA Yang C., Oksanen H.M., Bamford D.H.;
RT "The complete genome of a viable archaeum isolated from 123-million-year-
RT old rock salt.";
RL Environ. Microbiol. 18:565-579(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LN831302; CQH60385.1; -; Genomic_DNA.
DR RefSeq; WP_059057564.1; NZ_LN831302.1.
DR AlphaFoldDB; A0A0U5AHI0; -.
DR STRING; 1407499.HHUB_3199; -.
DR GeneID; 26659814; -.
DR KEGG; hhb:Hhub_3199; -.
DR OrthoDB; 56871at2157; -.
DR Proteomes; UP000066737; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833:SF9; POTASSIUM CHANNEL PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000066737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 242..364
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 384 AA; 39817 MW; 88CDCFA6ECB4C620 CRC64;
MDVPGAKRVT GRVAVALTLA VAALSVGVGI LGIVDPTANF GPVAQYIPPA ISQTAGFTGS
LTGFLMVMSA FGLRRGLRVA WYSTLVLLPI TAGQGLVQAT PYSVPLVVLS VVAFPVLAVA
RSRFDEPISL STSQLAAGGA LAGVQAYGTI GTWALRGERG FTGVNTMLDA FYYTLVTSST
VGYGDVTPVT QEARLFSLSV LVLGTASFAV ALGALLGPAL EARFASALGR MTQSDLESLD
GHVVVAGYGD LTEPILTELA ASGRQFLVVA RGGTDTSELR DRDIDVLAGD PTDEKTLDRA
GIERARAVVT ATNDDGEDAL AILTVRETYP DVRVVAAATE QENEPKLRRA GADTVISPAV
IGGRLLARSA LGDEHAEEEA ADLE
//
