ID   A0A0U5CZR9_9EURY        Unreviewed;       744 AA.
AC   A0A0U5CZR9;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Transport protein (Probable substrate cationic amino acids) {ECO:0000313|EMBL:CQH60115.1};
GN   ORFNames=HHUB_3140 {ECO:0000313|EMBL:CQH60115.1};
OS   Halobacterium hubeiense.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=1407499 {ECO:0000313|EMBL:CQH60115.1, ECO:0000313|Proteomes:UP000066737};
RN   [1] {ECO:0000313|Proteomes:UP000066737}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=JI20-1 {ECO:0000313|Proteomes:UP000066737};
RX   PubMed=26628271; DOI=10.1111/1462-2920.13130;
RA   Jaakkola S.T., Pfeiffer F., Ravantti J.J., Guo Q., Liu Y., Chen X., Ma H.,
RA   Yang C., Oksanen H.M., Bamford D.H.;
RT   "The complete genome of a viable archaeum isolated from 123-million-year-
RT   old rock salt.";
RL   Environ. Microbiol. 18:565-579(2016).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; LN831302; CQH60115.1; -; Genomic_DNA.
DR   RefSeq; WP_059057512.1; NZ_LN831302.1.
DR   AlphaFoldDB; A0A0U5CZR9; -.
DR   STRING; 1407499.HHUB_3140; -.
DR   GeneID; 26659756; -.
DR   KEGG; hhb:Hhub_3140; -.
DR   OrthoDB; 56838at2157; -.
DR   Proteomes; UP000066737; Chromosome I.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd00293; USP_Like; 1.
DR   Gene3D; 3.40.50.12370; -; 1.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   InterPro; IPR006016; UspA.
DR   PANTHER; PTHR11785; AMINO ACID TRANSPORTER; 1.
DR   PANTHER; PTHR11785:SF512; SOBREMESA, ISOFORM B; 1.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   Pfam; PF00582; Usp; 2.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000066737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        42..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        127..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        198..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        232..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        275..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        332..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        413..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          472..609
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
FT   DOMAIN          617..729
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
SQ   SEQUENCE   744 AA;  77755 MW;  2DE9560EC8BCBDE5 CRC64;
     MSDQELAKDL GPLAALTIGV GTMIGAGIFV LPGAAVRDAG PLSALAFLAG GGIALLTALS
     ASELGTAMPK AGGAYYYVNH SLGPLFGSIA GWANWMGLAF ASAFYMFGLG KYVVTFVSVP
     SVSLGPLTLV PAQVVALFGA ALFVGVNYVG AKETGGLQNV IVVTLVAILA VFTAVGAFNA
     DLDSLFPLVR EGKGFAQVLP VTGMVFVSYL GFVQITSVAE EIKDPGKNLP RAVIGSVVLV
     TFIYALVLLV VLAAVPNELV AGNDTAVVDV ARRLMGPAGA VALLFGGLLA TASSANASIL
     ASSRINFAMG RDKLVSDSLN TIHDRFATPY RAIGLTGVFI LVFVLVGNLE TLSTMGSTLH
     LVIYGLLNVA LVVMRTVDPP EYDPDFRVPF YPATPILGAI TSFALIAFIN PTIIAATAAF
     VAFAAAWYLV YARSRATKTG ILSQYLQANP ERAPDAAVSA AESLAPDGSD YRVLVPLANP
     ENETELITLG AAAAKANAGR VVAVHVVQVP DQTSLAYAND HLDEFTDAAG SERLLENARA
     DAEDFGVPVE THTILSHRSF EELFDAAETH DADLLVMGWG PDSHGSPGRA ESAVDELAGD
     LPCDVLVFKD RGFDPSRVVV PTAGGPDSEL SAAVARYLRE QFDSEVTLLH VADDTAAGRE
     FLETWADEQG LSDAELRVES GDVEDVIAAA AEDASMLVVG ATERGLLERL VTGSLVLDVV
     DEVDCSVVLA EQQRSRSLLE RLLG
//