ID A0A0V0SML6_9BILA Unreviewed; 1224 AA.
AC A0A0V0SML6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=TBC1 domain family member 13 {ECO:0000313|EMBL:KRX28112.1};
GN Name=Awh {ECO:0000313|EMBL:KRX28112.1};
GN ORFNames=T07_3556 {ECO:0000313|EMBL:KRX28112.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX28112.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX28112.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX28112.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX28112.1}.
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DR EMBL; JYDL01000001; KRX28112.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0SML6; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR CDD; cd14690; bZIP_CREB1; 1.
DR CDD; cd00086; homeodomain; 1.
DR CDD; cd09379; LIM2_AWH; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24208; LIM/HOMEOBOX PROTEIN LHX; 1.
DR PANTHER; PTHR24208:SF127; LIM_HOMEOBOX PROTEIN AWH; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF00412; LIM; 2.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00338; BRLZ; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00132; LIM; 2.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 171..234
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT DOMAIN 548..846
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT DOMAIN 943..1004
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 1005..1066
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 1075..1135
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 1077..1136
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 166..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1131..1184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 196..237
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1224 AA; 140586 MW; 42D3655F102F36E2 CRC64;
MEMLDDIDLN WTLESDSSNF RLLSFAEFAK DSTSSTPQDS FNFNTVNSFF TDSDDSGVNF
GDNDQSPFSL PHEIRGLRTP EPACDSNNVL SFESNSNQHR HSTTDLFAEN LNGHVAEPSL
QNAGNVYTPT NSVIVLATAY PPSNNQTKRY LPLKPKSESP SVLIVDSSSS MSKVEQNKMR
NRESSRQFRL RRKDYVTSLE AKISKLENEN LLLKRENDAL KSTVSNLLFE MENLKLELAS
RLESTSTVTI NESPKRRKDA VFVAVLLLMF TFNLSPAYFS SFTGKNTGAF DEHLQLHLIS
SRLSDANLKK RSYGNFLDRV NRTKREILNQ GEETASSYPC KSDSYLNKTE TFRLTMELNR
WANRHQYNKK SDKKQGAKSR VQRAKSRVKN RSTDAIFAFQ HDKKSLKLKK MFSNGKMNWN
YLKAVDWSHV LSALNRRNDT FYVVSLFKDY FVVPAASYNR TTRPRISLLA PFMPFDDSVP
VSFENIAMLQ IECEVMNTQL LNLRDLFSKS APPTQLYSQA KNNNSLAPPS ERHAFVNVSQ
SAFVIGIPDE SELRPICWRL LLNYLPTEKV KWPEYLKNQR KLYADLVEDI VIKWNSILDT
DEHSCDHPLS AEPNSVWSQY FRDNEVLVQI NKDVRRLCPE MSFFQKITQY PCQAIVKNGA
LALSQRVLTS TLRAEHLRNH RSGANNLVED CSKRGNDDYF TIDKGKETHW QVVERILFIY
SKLNPGVKYV QGMNEIVGPI YFVFASDSQW QEHAEADTFF CFQNLMSEIK DNFIKTLDSS
NVGIDHQMRA LYSLLQRVDP VLHQAMTEVQ QLCPQYFAFR WLSLLLSQEF LLPDVIRLWD
TLFADCRRFE FLLYVCLAML ILVRNDILTN EFSVNVRMLQ NYPPIDIVSV IKLASEIRAV
MEDRHPCVQG KLNLPLPESK AMKSDPQKEQ HHIGHKMMKL TEEICSGCGN LIYDRYLLQV
NQQLWHVNCL RCSSCTALLD KLPSCYLKED KVFCKMCYQR QFSVKCDRCN QVIQSNHWVR
RARQYVYHLA CFACDSCQRQ LSTGEEFALQ DSRVLCKQHY MELLEGDNGK VHHKQKTKRV
RTTFTEEQLQ ILQANFQIDS NPDGQDLERI AQGTGLSKRV TQVWFQNSRA RQKKCQGVKA
KSNSSHPNQS SQDSYDESSP SGPVSEPVTS HSIRSSPSQE DFSDLQYITD ANEANVSMET
DHIHMNAMFD SIDSVSSSVT NSPC
//
