ID A0A0V0U100_9BILA Unreviewed; 2421 AA.
AC A0A0V0U100;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 03-MAY-2023, entry version 30.
DE RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};
GN Name=beta-Spec {ECO:0000313|EMBL:KRX44567.1};
GN ORFNames=T05_5492 {ECO:0000313|EMBL:KRX44567.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX44567.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX44567.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX44567.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spectrin family.
CC {ECO:0000256|ARBA:ARBA00006826, ECO:0000256|PIRNR:PIRNR002297}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX44567.1}.
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DR EMBL; JYDJ01000093; KRX44567.1; -; Genomic_DNA.
DR STRING; 144512.A0A0V0U100; -.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProt.
DR GO; GO:0008091; C:spectrin; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:UniProtKB-UniRule.
DR GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-UniRule.
DR CDD; cd21246; CH_SPTB-like_rpt1; 1.
DR CDD; cd21248; CH_SPTB_like_rpt2; 1.
DR CDD; cd10571; PH_beta_spectrin; 1.
DR CDD; cd00176; SPEC; 9.
DR Gene3D; 1.20.58.60; -; 12.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001605; PH_dom-spectrin-type.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR016343; Spectrin_bsu.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF447; SPECTRIN BETA CHAIN; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00435; Spectrin; 17.
DR PIRSF; PIRSF002297; Spectrin_beta_subunit; 2.
DR PRINTS; PR00683; SPECTRINPH.
DR SMART; SM00033; CH; 2.
DR SMART; SM00233; PH; 1.
DR SMART; SM00150; SPEC; 17.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 13.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Actin capping {ECO:0000256|ARBA:ARBA00022467,
KW ECO:0000256|PIRNR:PIRNR002297};
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203,
KW ECO:0000256|PIRNR:PIRNR002297}; Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR002297};
KW Cytoskeleton {ECO:0000256|PIRNR:PIRNR002297};
KW Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 56..160
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 214..319
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 2274..2384
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 2175..2211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1036..1077
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1361..1420
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1605..1639
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2184..2199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2421 AA; 282121 MW; 7A9F6B79F2DC990B CRC64;
MNKSCEYLHA NNAHDSRSTT DSRGDDSSSL LLLSEEDLDL YTMDKIVKIL KDERENVQKK
TFTKWVNSHL ERAQCRIQDL YTDLRDGKML IKLLEILSGE RLPKPTKGKM RIHCLENVDK
ALQFLRLQHV HLENMGSHDI VDGNPRLSLG LIWTIILRFQ TVSSSILVRI SLSVVLLNLG
ESVVSVCDNC DRFFMACVQI QGIELFDTES QETRSAREAL LLWCQMKTAG YPNVNVRNFT
TSWRDGLAFN ALIHKHRPDL ISFEKLQRSN ALHNLKNAFE VAENQLGITS LLDAEDVNVE
MPDEKSIITY LVSYYHYFNK LRQETIQGRR IGKVVSELME NDVMIEEYER LSSDLLQWIK
KTIEKLNDRV FVNSLVGVQK QLTTFNNYRT EEKPPKFVSK GNLEVLLFTL QSRMRANNQK
PYLPREGRMI SDINKAWENL EKAEHERELA LKEELIRQEK LEQLAARFDR KAGMRETWLA
ENQRLVSQDN FGSDLPSVEA ATKKHEAIET DIYAYEERVQ AVVAVAQDLE AENYNDIDRI
NARKDNVLQL WNFLLELLMA RRVRLELSMV IQKIFQDMIH VLGWMEELKA RMLSDDYGKH
LMGVEDLIQK HQLVEADVNI VGDRLKLVCQ QAEKFTHPDG PDGSGYQPVE PALVQERIQM
LEAAYKELLA MVEQRRQRLE DSKRLCQFFL DAEELEQGFK ELEQVLSSPD VGHDVVSVNL
LLAKHKSVED QIASLQRNKN AVIDIGRGLI GENLPGSSDI QAQIDHIEEM WQALRTLANL
RKQRLVGAVD YYQLFSDIDD NEAWLLDSLR ILSSEDVGKD EPSVQHLIKQ HDGVTEELQN
GRNSLDQLYA QAEQLPEAAR AGPDVADRLG QIEKRYAEVM ELGSMRKQRL LDALTLYKLF
NDTDNLEAWI DEKAKLLESL KPADDLEEVE IMRHRFETLE QDLNNQSAKV LTVNKLSRQL
LHVEHPNSDA ILQRQNRLNA RWAQLQDMVR RKRLELDQAH RLQTFRIDCQ ETVTWIQDKT
RVLEDTEELK DDLSGIMKLQ RRLSMMERDL GAIQAKLDNL EQQAVRLQQE RPEEVEAIRE
NIARIQYVWD RLTGKVREYE AKLDEAGDLQ RFLRDLDHFQ GWLSSVMRQV ASEDEPQSLA
EAEQLLSQHS VIREEIDGYA EDYAKMRMMG DRVTQDQTDP QYLLLRQRLD GLQEGWQELH
RMWDNRQAML SQALNLQMFL RDAKQAELLL NQQENYLAKD EAPTSLEQAE TMLKRHGDFL
TTMEAGDEKI RAVVVFGNQL CEDGHFAADR IHKKVSNVHE RRELNREKAN SMTERLREHV
ALQQFLSDCE ELRRWIEEKM IRAQDETYRD AKTVHSKFMR HQAFEAEIQS NKERLQRLQE
ACVRLIAEKP QLDSFVDPHV AELTAQFDEL ESKTKEKGQR LFDANREAIY VQACEDMTEW
VEAMEKQMGT EDVAQDLATV NVEIQKQQLI ESEMLKRVQQ VCQLQAMEPQ LEELRPEEFD
AIKTHRLTVQ EKFSKLQAPL EQRRQLLERK KEAFQFLRDV EDEKLWIADR RPMARSPMLG
DTLFDCHRLQ KQNQSLKNEI ENHQPWIQRI CDNGRKLIAS GHENAPEFEA KIKELLEALE
ELKKDVEKRR ERLAESEKAH QYIYDANEAE VWMSEQELYM MTDDRGRDEF TTENLIKKHE
RQRQDVEQFA DTIRDLADRA QKLIAEHAPM SDTIAIRQAQ IDKSYAGLQD LSRERRHRLG
ETLQLFNLHR QIEDILQWIA EREVVAASQD AGQDYEHVQM LQERFRQFAK DTETIGTERV
SNANEECDQL MAVHHPDAPT VALWKDNLNE AWENLLELMQ TRAQMLDASC QLHKFFHDCR
DTLSRILEKS HSMPEDLGRD ASSVSALQRK HQNFLTDLLS LESQVKQVQA DARSLQASYA
GDRALEIQAR EGEVLNAWRL LQANCEGRRT KLLDTSDLFR FMQMVRDLLL WMEEVKREMN
TQERPKDVSG VELLMNNHQS LKAEIDAREE NFSSCIALGR DLLARKHYAS SEIEKKLIKL
TTERAEMMRR WEDRWEYLQL ILEVYQFARD AAVADAWLLA QEPYLLSKEY GRTLEEVVKL
IKKHEAFEKS TIAQEERFQA LEKLTTLELR AQEYLMWLRM GNRLALADMA QCGLRFMEAM
ESEMFELKEL QRRQDEQERL RRTGSPRTST PTRSPEKLET TFPAESGGRT ETTLGVDEGK
LFSYFLLVQD IFTRCCHERE RRRQLHSSES PGWRISLSRS KYFDANDSVG TESAEGFEGH
LIRKHTWETL DRKASIRSWD KLYCVIRGSQ LEFYKDHKHR EDGELYRGET PINLVGWNVE
IASSYTKRRN VLSLRSPAGF EYLLQARDED DMLRWLHQLR TAVGILETST SSSGKASTLP
AAQQPSAKKR FFGTLKKKQA L
//
