ID A0A0V0UEW7_9BILA Unreviewed; 1061 AA.
AC A0A0V0UEW7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Apoptosis-stimulating of p53 protein 2 {ECO:0000313|EMBL:KRX49919.1};
GN Name=TP53BP2 {ECO:0000313|EMBL:KRX49919.1};
GN ORFNames=T05_4027 {ECO:0000313|EMBL:KRX49919.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX49919.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX49919.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX49919.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX49919.1}.
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DR EMBL; JYDJ01000011; KRX49919.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0UEW7; -.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0002039; F:p53 binding; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047163; ASPP1/2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24131:SF10; ANKYRIN-REPEAT, SH3-DOMAIN, AND PROLINE-RICH-REGION CONTAINING PROTEIN, ISOFORM B; 1.
DR PANTHER; PTHR24131; APOPTOSIS-STIMULATING OF P53 PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 873..905
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 906..938
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 972..1036
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 410..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 755..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1040..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 303..382
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 554..572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..774
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..796
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1061
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1061 AA; 116935 MW; 78A1B6E06407F2FC CRC64;
MNGSLWKVEA TSRMLLQANA LKSRCMRRSI KPRSSRLVWL KQPVVSSDRQ GQWDVNIDAM
TGATVVQLIC QRPTVSDTKV VVWWSFGKLK LATASCATSK FNVDRTGTSN HRGRQLCSAN
GRRKGRAPNF HTVIGQPEMM HVTVVVQLPG KQVAEVPLLP DSTAADVIRQ LKLNANLSDD
YFLTADFDGY DKLFDAEERL YQLVKKHILG GGRKNDVQFY LRKKKTITSG LNTSASSSQS
DGKNEALPEM YKTNPDFGDL FKMPVSQLRR IALHRRALID QNCNTINEKN RKLNSFLTSS
GVDLRLQQKL RQLEDRLALE EARFKKLTRL KEELNNYSLC YKSLVQQLDL LKMKMRNKKT
EVELADQKVE ELSRLLAKLK LQRILLAKRA EISLYDSEIG DLSCALSLPT TGSGSGADPG
PSSGPGPGPD GQASSKLSVG SECSRVQGSR PKAAVEPFKI DTPDQDVECC STEEAAAESG
SKLDQYVRSK GFRTAFFAMQ RALVEDATGD GRSVELPSDS DDHDVVMVDG GQPPPSAGPT
EPLVKFVHSN ASRRSNVRSE LADSSQSPPP DLIPASEKSK FLGQGALASA SDAALGDIVK
AETDKIHLRS DTLRAAKRRS WAEHHANLAT SDETEHIRLL LCRELKKGKT SVNLSWILDQ
LDSVGAATTS TSTSTTNALL SEPMRSSLSP SDEHLNYCRA KVTSSTTNND DDTKLTLDSL
TAVCCPQISD KLLCDSVEIE KNGKDDKVEV KEQLLEQQPQ ENDDDDDDDG GKEEEHEREE
ITIVVVDEEG PEVERRQRSG NGTTSTNRRE AEPKPRRGIL QGTSARCGDG PVRPRGVHFD
PLALLLDAAL EGELDLVKRC SKQLPNVSVC YEEGITALHN AICAGHYDIV RFLVEAGADV
NAQDSDGWTP LHCAASCNNL PIVKFLVENG ACIFASTLSD EETPAAKCEE TEEGFVGCSQ
FLLGLQQRMG TMNGGIVYAA YSYDPERDDE LGFEKDDQLR VLAKDLDGFS GWWRAFDPKS
GREGYVPRNY LSLYPRPSQL RFTTRGGKND QQEESRAKTA Q
//
