ID A0A0V0VN62_9BILA Unreviewed; 1260 AA.
AC A0A0V0VN62;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Retrovirus-related Pol polyprotein from transposon {ECO:0000313|EMBL:KRX64960.1};
GN Name=pol {ECO:0000313|EMBL:KRX64960.1};
GN ORFNames=T09_1605 {ECO:0000313|EMBL:KRX64960.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX64960.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX64960.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX64960.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX64960.1}.
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DR EMBL; JYDN01000020; KRX64960.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0VN62; -.
DR STRING; 181606.A0A0V0VN62; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0019899; F:enzyme binding; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR008042; Retrotrans_Pao.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF05380; Peptidase_A17; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS50878; RT_POL; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 219..233
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 381..559
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 1260 AA; 143726 MW; BE38DE4DC43F0031 CRC64;
MDEQKAVLSA QQSTESAQMM GTARFPIGAH RPFNPEEGTW DTWILQFRSY LEINLINDSN
LMRSCLLASL TLNVFEELRR SCLPTTPYDF TYDECVAKMK ELYGRRVILM RERASFFRIT
QSDHQTPKQF ANCLREAAGH CNFESFNTEA ALVLQFINGM KNEEIKLRLL AKENIKLDEA
LSFLEMYEEI HCCSSRVTMQ ECHAVEETKG LKSGGVSNCF KCGKQGHLAK VCKHPQKLGK
SQKQRPLNSW KDHKLYADGI YAVTERAHNF EVTVKINGSQ FEWSWTLELQ LPSFTGHQVN
LKGETMVTVE GDTGTRKLVL RVAKNGATNV MEVFEDGLGH CTKVKAHVKL KDGVVPVFRK
PFPLAFAMHD AVGKELERYV DMGVLTPIDR SAWAAPIVTG KKPNGMIRIC ADFSTGLNDR
LMVDSYPILR PEDLYQTLRG GKTFTKLDLS EAYLQVELDE ESKKILVINT HKGLYHYNRL
PFGVASAPVI FQRVMDTMLA GIPNVAAYLD DIILTGATDG EHRRTLKLVL GRLKEFGLRI
RKEKCTFFQR EVEYLGHILS SKGIRADPKK TAAIVNMPLP TNIAKLRSFL GMCNYYTEFI
PKLAEMCSPL NQLLRKDARW KWTAEHTKAV KRVKRLLNSP LLLTHYHPEW PIVLAADASN
EGIGAVVYHR LRDGTVKVIA HASKTLNAAQ SNYGQIEKEA LALVYGVKKF HKYLWGRRFT
LLTDHKPLVS IFGSKKGVPQ MAACRLTRWA IALMNYSFDI EYRSTKNFCQ ADCLSRLPSS
SDELFDANFD HREAEDELTL PVTARVIAEA TEKDSVLKQV KQFVLSGWPE KCPREELRSY
FIKRTELSVF YGCLIWGIWT VILMKLRSRV LMKLHETHPG RERMVSMARQ FCWWPAMNKD
IEMKAQSCEG CATAQKNPAK RLSLPRLELM GALVAARLVH YTQRALSLPI HSITCWCDSE
VALSWVRSAA SRWKPFVRNR VEEIQQLVEP ASWRHCSGKD NPADWLSRGV TVTKLAEGNV
WWHGPTWLAR PQQAWPRRQE NHERNPLIPP GEERTSKHAT CALMTVQTTE EPLHPGRYGD
IEKLFRISAY CRRFAKNCRS SVSERHGGNL TAWELHEAEE MWVRRTQEEE FQAEIQALVR
HGRVAEHSRI RQLDPYLYER GVLRAGGRLV NSYLPASMQH PAVLPGNHEL TRGLIRRCHQ
RQPHAGGRSQ VKRVTRECLV CRRATARPTQ PRMATLPRDR VVEAPAFSQV GMDFAGPLYV
//
