ID A0A0V0XNQ5_TRIPS Unreviewed; 373 AA.
AC A0A0V0XNQ5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 19.
DE SubName: Full=Rab GTPase-binding effector protein 1 {ECO:0000313|EMBL:KRX89583.1};
GN Name=Rabep1 {ECO:0000313|EMBL:KRX89583.1};
GN ORFNames=T4E_8748 {ECO:0000313|EMBL:KRX89583.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX89583.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX89583.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX89583.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX89583.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDU01000193; KRX89583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0XNQ5; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd15739; FYVE_RABE_unchar; 1.
DR Gene3D; 1.20.5.730; Single helix bin; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003914; Rabaptin.
DR InterPro; IPR015390; Rabaptin_Rab5-bd_dom.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR31179:SF7; FYVE-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR31179; RAB GTPASE-BINDING EFFECTOR PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF09311; Rab5-bind; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 296..354
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT COILED 2..40
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 130..182
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 211..259
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 373 AA; 43825 MW; 46141EB99055B53A CRC64;
MFQETERRLR QQLTALQNLN ERYKSELSAA RLNHKELDSS VNEMMDKVSK QLTDLRDIFK
AVELRHTELE GYFKGETTNI RRELSEVIAS RRKIEDVYQT LSDQYDHLLG RHRQGARQLE
EEKIDLPQDV EELQLLCLQL KEELIETRTA KEHLEETLMS EIVLLKAEIA SEKQAKEQVE
ASLADDICHL RSQLDCAQNC LLERESLYKW KVEAQSQFDK HRRRISELES HVQELEKEKL
QAKELIQEGQ RRAQVLQQEL DNCVQVQRDF VKLSQSLQIQ LEKIRQSEHE VRWEDDDDVL
MCRGCKQLFN RHRRKLHCRH CGRIFCDPCL SRTVSSGPQR KPAKVCEVCH TLLVSETAPY
FSVEVPHSQL DGA
//
