ID A0A0V0Y4C7_TRIPS Unreviewed; 1462 AA.
AC A0A0V0Y4C7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 4 {ECO:0000313|EMBL:KRX94866.1};
GN Name=PPP4R4 {ECO:0000313|EMBL:KRX94866.1};
GN ORFNames=T4E_2137 {ECO:0000313|EMBL:KRX94866.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX94866.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX94866.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX94866.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX94866.1}.
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DR EMBL; JYDU01000065; KRX94866.1; -; Genomic_DNA.
DR STRING; 6337.A0A0V0Y4C7; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR004299; MBOAT_fam.
DR InterPro; IPR039918; PPP4R4.
DR PANTHER; PTHR21467; PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4; 1.
DR PANTHER; PTHR21467:SF0; SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF03062; MBOAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1073..1098
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1110..1132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1174..1191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1212..1234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1254..1277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1332..1348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1354..1373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1394..1414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1436..1454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 205..242
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 372..408
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 726..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..841
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1462 AA; 166665 MW; C3686728E95B77B1 CRC64;
MLYSIIRELN SGKIFSNKIL ITSFTIYLTF GFYSSTPLGI DIAMWTTCRE CERWIRKPTN
LRGAKFAWLF GQQNQTTQRC STYGGSNAVL IELRNGHPIR DLRIVRAAWM EMIIDVIDVI
STPLLTSEVL PTALQKSQQM NSIYARLFGG KLLGQIAAKI SPDEVRRKIL PVVQAQCQDP
DSRIRATACQ QLSTIVFSAD IKSILLPMLI ELNKDEDETV READFEAIVS VLFRFDKETR
SNIFMPIIKK CAEDALLTKS TSSLLILAKV LKKLCESLDG KMTNSEKTWI IEMFQQLSLL
GTEEKPDGEE TVNGDYVWNA LFSPYFLLRK AIDYVSKRMD PNIASITCRR SAAAAISILT
ELITLNEFRT SLLPVYRRLC QDTDSEVQKQ AALSFHIIAK FFDPHSSELM DCFIDLIYSG
DTDVIEGLAK HLDETLSYMY KTSSSKQDSE IPTHRSHPSQ LTRVLLACNR LIRNSSNWRC
HEQYILALRS LLSCVGEDVL TTSFVPMLKD EVLHVQAIPC RFACLKTMLT WISQLKCSKQ
VQSLVDFFIS CLQCHKSAKR RVLYLVACEM AIKMGLVELF KEKLLYPALK MTDDPVIDVR
LKLCSLFPVF KSALNLPKEN NLLLALQDAL SKLDATGKSV TFKRIRAQVL AEIGETPRNE
TNIHAENTRL PDKDKVKKPT LKTTAVASVQ PIVAVHPTSI PPAPPQQQQK LKNGNMLNAN
VKKLDKPGEA LSDAKSGHIP RASSRRTAVV QPQQLLHRDA SPRPTGQSYE RVRTRQMTDS
KPTSVDGKKA SNIPVKAKSV SQISTSENKT AAYKRTSVDK SKSTQKTYSN ENLTTPNQHP
APEKRKVTPV SCNSSAISKK NVEAEKSKNS ESQNAPPQPV ALTKGGPNGK KIVVKPTPIL
KMNKPSVASK PLRTPAVICT GSVMKSIAKF EQSMAKHQES LMKRTTSYQY PRRMNSGEVN
SVEQKKRQSF KYPSLPNGET AFYFAVISCT IFYTWYKVFQ LSNEPQVQNN TVAPLTNSHL
WLIGDKLKDT SNYEWQHWIV WVREALPWYF VHSLLFNCTE KLLRTTVWKR FMIVYWIFAS
WYLFATHIVL TVFTAATFMY CAAYWLRSKL AVWTITLGIL YVAVEGIVDF AADEDAFKSI
SFIGYKMLQC LSFCLDLIDN RAVCDHFFDG FFKLAWYMLY LPYQLSLIVI YKRFQPDMEC
RNSRQMNLSR TLLFGIRILF WYCFTELLLH HLYFEAISMN IELLTSIPLD TLCCIGALLG
QFFHLKYVVI FGFPAFFAKL DKMTPPNGPI CISRVTLYSN IWRHFDRGLY EFFKEYIFLP
IARPSFRIER KLAGLLLSFS FVLVWHGFRH SCMVWVGLNV VEILIENFGK VIYSFQSVQK
LREKLISDQC FRRILALLQV LPLSFGLYSN YYFLGGSKVG KVFVDRIFWG ETYPKFKLPA
LILVTLGYCF NHLAMEINSR LN
//
