ID A0A0V0Y5V2_TRIPS Unreviewed; 1423 AA.
AC A0A0V0Y5V2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Protein crumbs {ECO:0008006|Google:ProtNLM};
GN Name=EGF1 {ECO:0000313|EMBL:KRX95613.1};
GN ORFNames=T4E_7081 {ECO:0000313|EMBL:KRX95613.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX95613.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX95613.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX95613.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX95613.1}.
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DR EMBL; JYDU01000054; KRX95611.1; -; Genomic_DNA.
DR EMBL; JYDU01000054; KRX95613.1; -; Genomic_DNA.
DR STRING; 6337.A0A0V0Y5V2; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 7.
DR CDD; cd00110; LamG; 3.
DR Gene3D; 2.60.120.200; -; 3.
DR Gene3D; 2.10.25.10; Laminin; 15.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF07645; EGF_CA; 3.
DR Pfam; PF12661; hEGF; 3.
DR Pfam; PF02210; Laminin_G_2; 2.
DR SMART; SM00181; EGF; 19.
DR SMART; SM00179; EGF_CA; 10.
DR SMART; SM00282; LamG; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 14.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS00022; EGF_1; 14.
DR PROSITE; PS01186; EGF_2; 11.
DR PROSITE; PS50026; EGF_3; 18.
DR PROSITE; PS01187; EGF_CA; 4.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1423
FT /note="Protein crumbs"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007437756"
FT DOMAIN 29..65
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 67..109
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 143..181
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 185..221
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 224..260
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 262..298
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 301..337
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 357..396
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 397..436
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 449..483
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 485..525
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 527..570
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 573..746
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 751..787
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 793..1017
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1013..1049
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1239..1276
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1278..1309
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1310..1346
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1349..1391
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 33..43
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 55..64
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 99..108
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 152..169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 171..180
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 211..220
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 250..259
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 288..297
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 327..336
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 367..384
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 386..395
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 426..435
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 473..482
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 496..513
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 515..524
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 719..746
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00122"
FT DISULFID 777..786
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1039..1048
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1266..1275
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1336..1345
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1381..1390
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1423 AA; 155959 MW; 4DC142EB8CDD37B7 CRC64;
MLAIRWQLFF ACCILSSSIQ ASNAIASSST IECVHHCLND ASCRAANGTI LKCICPNGFE
GSRCEIRSGK CPADYCVNGG TCHVIGQDSY GEVIFGCHCL DNFSGDYCEI ESKCETACIS
DSVCRAGSCV CRPGSEGTPG NCVPKDCNLN PCLNNGTCVA NNDDRTATCN CQLGYSGLLC
QLDFVTVDCP PNTCPDGHLC EKFQDEIRCI CPKGFAGISC NVPLGSDCSI DLCMNGGTCV
KGNPVSSCRC PAQFDGPFCQ FDVNECLTIR PCGRGNCTNT HGSYTCNCEP GWTGHNCLEK
IRHHCQNGTC QNDGLCVEQE DGFRCVCSDR YAGKFCEIES TAFGKKSTSS PLADDPESSS
CGSSGKCFNG GICKVEPDKG GSRCACPKGY GGKWCEIELS CNHIPCLNNG TCIKMPGNAV
GVGCKCLPDY YGSFCEFFAP KLAIRFKPTS NFCFYNPCQN DGLCDESTQS CVCGPGFQGV
LCEQDLDECD HRDAYCPLQF SVDCVNQHGD YQCECKPGYA AKNCSIRLNA CDDHRCADRQ
ICTVTWDSGT EKQQAQCECA PGYTFMPSCL QSTVASFSGQ SMMVDITSNN HTATATYQLE
LQFRTTLENG FLIFGDDLFN SNIFQVLLLD GQIQALWSGK RVRIEQKVND GTWNRLSLSW
HADTMLLRLQ RSKAGDVHLK RLSSGGALLA SAVASTKFGG TPLEKQHPYY PDVGNFVGCM
RDVIVNGKLL IPEKMGASAV NVGWTCPRRQ DRELCDETAC PARSHCVDVW NQGRCVCDRP
YLMPNCENSL PEVTFGFGRN ISFVMVDIAR AYSIALHDRL DLSMLIRSTA LNGVICYIGT
AIDEQQHFRF NEHHAGCCFI GLELRDGYPV LVSSWNSTSP TVVSSENRLN DGRVHLIEIK
YRPYVLKVLV DSQPAFINWF DDNGQTTANP LSPEQLIIGT HPILVTNRTI VDHSIAVESF
STFTSFKGTI QDVRINDDIV ELAPVADDVV SSSMLGKVNG RITRHSLLLG TQSDDLCASK
PCANGAQCTV TFNDYECQCE PAWVGKNCSI PHPCLSEPCP VDWQCRLKPH TYEHVCLNSI
TFSEQSRALF QVSNGPNAAD HVAFSIRTRT KHGPVMSIRS TARLNEMQVF LKDGRVLVSR
LVAGEKPILL DSLRPIADAQ WHHVHVGLWP NLTMELDQNV MMIAGPAIPL PSETVWHFGS
YTDQDHIPTE RSPEQMRTDE SFGVFRKISF DHLTQGCQSN VQCGLTDICE NGATCSDEWN
LVTCTCLPGF SGLKCENDVD ECEYGWCKHG STCRNLIGDF ACDCLPGWTD VDDCAFHPCM
NGGTCVDGEN EFHCLCTANF TGPTCENRHY FNCSSGPCEN GAQCEDAYSL VRNAKPYVCH
CGAGYTGERC ELEIDYCATV NIANMKLTNV PAHRVRMVER VQI
//
