ID   A0A0V0YEH5_TRIPS        Unreviewed;       312 AA.
AC   A0A0V0YEH5;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Pyruvate dehydrogenase protein X component, mitochondrial {ECO:0000313|EMBL:KRX98455.1};
GN   Name=Pdhx {ECO:0000313|EMBL:KRX98455.1};
GN   ORFNames=T4E_6219 {ECO:0000313|EMBL:KRX98455.1};
OS   Trichinella pseudospiralis (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX98455.1, ECO:0000313|Proteomes:UP000054815};
RN   [1] {ECO:0000313|EMBL:KRX98455.1, ECO:0000313|Proteomes:UP000054815}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS141 {ECO:0000313|EMBL:KRX98455.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|ARBA:ARBA00001938};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00007317}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX98455.1}.
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DR   EMBL; JYDU01000021; KRX98455.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V0YEH5; -.
DR   STRING; 6337.A0A0V0YEH5; -.
DR   Proteomes; UP000054815; Unassembled WGS sequence.
DR   GO; GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   GO; GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; IEA:InterPro.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 4.10.320.10; E3-binding domain; 1.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR045257; E2/Pdx1.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   PANTHER; PTHR23151; DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR23151:SF90; DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR   SUPFAM; SSF47005; Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex; 1.
DR   PROSITE; PS51826; PSBD; 1.
PE   3: Inferred from homology;
KW   Pyruvate {ECO:0000313|EMBL:KRX98455.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054815}.
FT   DOMAIN          21..58
FT                   /note="Peripheral subunit-binding (PSBD)"
FT                   /evidence="ECO:0000259|PROSITE:PS51826"
SQ   SEQUENCE   312 AA;  34902 MW;  BA2170A9E571EB7C CRC64;
     MSAYGKMLAS LTKSKTPAFR LTGPAARLLL LEYHLDPLKV RSTGPRNALL KCDVLQYIAS
     HKLSKVPADQ GPPAAVQQEM KFSKRLARSF TDMPIVQLMK EAADQYSHSK HTIPHSYETA
     DVDVTTLMNL VQQGDDDDRE PSIFSFVIRA CLLALKKVPE VNILASGDDV FTSPSVNIGM
     NVISNDLFKM VVIRDANLMS AHEINLKRKV EYCELEEKVY SGTLTDDDCQ YPTFSIINLA
     DMHVTKCAEV LLPPQCALLS FGEVYQTVSN ENVRCYRVRA TLSYNNAVIR DEAALEWLNS
     FGNFLQHPIL LI
//