ID A0A0V0YEX7_TRIPS Unreviewed; 2636 AA.
AC A0A0V0YEX7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Translational activator GCN1 {ECO:0000313|EMBL:KRX98910.1};
GN Name=GCN1L1 {ECO:0000313|EMBL:KRX98910.1};
GN ORFNames=T4E_5255 {ECO:0000313|EMBL:KRX98910.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX98910.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX98910.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX98910.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GCN1 family.
CC {ECO:0000256|ARBA:ARBA00007366}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX98910.1}.
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DR EMBL; JYDU01000018; KRX98910.1; -; Genomic_DNA.
DR STRING; 6337.A0A0V0YEX7; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 6.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR23346:SF7; EIF-2-ALPHA KINASE ACTIVATOR GCN1; 1.
DR PANTHER; PTHR23346; TRANSLATIONAL ACTIVATOR GCN1-RELATED; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 4.
DR PROSITE; PS50077; HEAT_REPEAT; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1324..1551
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 1493..1530
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1569..1607
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1611..1649
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1958..1993
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 756..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..791
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2636 AA; 296370 MW; A247772B9926F1F1 CRC64;
MATTHKNNVK PIAHKTGNVI NSEIVSLKSS FQLMHYDIYE ALLSRAIFSD RKDVKFNTIQ
ALSQILKGRQ VNVFRYVSRV ITRLMEPFTQ NPSHSIRHAA ITALHVLKVV FPTKKNIIPA
ESHRHFMKYL KSIGICCYLI ITCGDIRFYR SALRKIFYMM KQSSIPTNIF VKGITAEGEV
DLSLVFVMLY DLRFETEFRG WMEDALNGYV RIVLQVPDGA EIEVLNCWKS VMSKVTLKEF
EEYLLPQLIH GMKKHIRSTI KAYAYLFDQL KIDLSEFVYD LLPSLIHYIC SKDELMKQYS
ISAVSALVKR LEKTEAKQTA LSGVLGLITD RPPIANTIDG KLAVLECVRK SSESLPENSK
EYFWNVILRL IGLIRTEVHD EVQKQCLKAI SKWTADSWNL SLPNELLQLF EEFGKRWNTA
ANSLSYMECI SSCYSRRGFK KNSKLAGLLV KIIETNMNLM NQPKRVLEAA YACKVLLHHF
SLKFDTEMTK VIYWIKEKHE FTSNKWWSSN DFDVWMTVMS CIEMVIVQSF DEISKRSLDE
YCRAFLCLLT HSDYKIRRNA EECLYRLYDK PIGPNLAVQL LKTFSSTLSS EMFVHYMNKK
QDSMTVDSSA ENRISRILAT VVVKLCCRNF SPSIQLIIQA LICLSRPDIL DVAPKFWDSI
LKFYNFTPAD YVREHHVQLC TLALRAEQKH AAEIAKQIFT RCDMHVFRDL LHKSAEMALD
ETVMQASIEA IDKSKTSNVD EESQYSWKSV FSKSSSGKQA KHATKEGSSK TKKSFQSKQE
RRVGLSKEGG IQVDNDHGAD LDKLLMNSVH GLDLIRAAIE SNSPHLKRNV QKIVETLLKV
VQCELLSSKA VDCWLSLVTR MFPKSEHVLA FRCAHATLRL LNCCAPLDKQ WTEESAISQG
RGVVEKLHAA VFCGSDDDDC DSLTESYAAL PLTMSVFAVC FPLVKQMILM MLNDEKEEDF
VCSLLSFIEI QVDKKAHKCQ VFEEENLPAS EIFELMCDNI CIASSFKVRQ LGASCLYNTV
EQLAEGNRLP DIDAAVVKMI QLVLDKMFTT IDYAVKEIFL KSLQIALCIV EVDSLSDEIL
TKLYALKFDM NESVASLANM IWESSRLELQ PNSLHVFTEM LNNPNGEIRA MVATAICNAM
KSGVYPLAVL LNHLNEIYDQ LADKASSLTD DFGRVIDDEL PNTVFSLKMG IASSLLRLSS
LIKENDLPKL LNAISARALN DNFGEVRFAM LNAAIEAVKL HGKNHVNFIF EKIENLLNCP
NDAAHDPLRM AAVILSGSVA QHLDKDDGRV QMVFVRLIEN LSIPSQDVVQ ETIASCLPPL
VPSVYREVPN VIRNFLQLLF SNANYGERRG AAYGIAGLVK GMGILSLKKL HIVSELQDAI
ADKGSARRRE GAVICLEVLS TILRKVFEPY MLLLTSNLLF CLGDVDRHVR QAANDCAKIW
MKNLTPHTMN MLLPRILDGL NADSWRTKCG SIDMLRAMAY CAPKQLSISL PQIVPNLVEL
LFETHELVQQ SAVQALSTVA KVIKNPEILN ISDSLLVALE NPERTENCLK QLVHTRFVHY
VDAPSLALVM PVLTRAFEDR SSETRRMAAL VMGNIYHLTG NEEVNPYLPS ILPGVKKNLL
DPIPEVRNVT ARAMGLMVKA AGKEKFADLL EWLRGMVVCK SSGINREGAA QGLSEVIGAI
GEDYLEVIMP QLFDVSTSAG AEAHVRDGFM NLFVYLPMVF GNKFLPYLDT VISIILKALA
DESEFLRESA LRAGKRIVHL YSTTATTKLL PSLEEGIYNS NWRIRLSSLQ LLGELLFKII
GVSGKMTTVG FEEETFGTAL SFQSIRQKLG SEHSDRIFSG IYITRFDELT SVRNMASHIW
KVVVVNTVQT LSEIMSTLFL QLLNCIGSSC VDLQKMSSNC MGSLVGTVGD RVFYDIVPIL
ERDFSNEGAE QRHGVCLALS QIMQNTNRET VAPYAQRLFP TVLRAMCDEV PEVREAASEA
FVSLYLSTGP KIVPFLARPL MENMSNPSTR SYFLDSLQQV MNTRGRVLLI HFIPNLCSMP
SNSEAIGKLF SRAPDILAQY LHQVLKAMFS SLMVSHGHNT LDITLEHFAL IVGAIHNKVS
MDQAFRFVHE KLNIREKRKC YISAVMFSAL CSHAQLPISE FGGEMIACGL SFYKLDNENI
LHIIGNSIGE CFRKLDSDQS LELLPSLARP LLSLINEMEL GDSSSAGGLC SELTVSPIVS
MLRSCLISGG SEVRRQLCVE LLFKMVAVCS ESSLHPSGVM LVGAMIRTLG ERHANSIRTP
LFQCLLALLI KIPTVMKCFA PQLQNLFLRL LNEQSSCAIR LIAAQGFGEL SKLAERRNLV
LQSLLNSLGT VEHPELKEAH LIGIRCVLLN AIGNQLDAEI ASKIHQAVLT KVVSSDEGHR
VACASLLSVL MCHFCTDKEL FFTLNRMTSF QNYQQASDDE NHFTGTLIML ILKIDAQKLF
QQLSKPVYNF LLLLIGSSSI TLMDTGLRAI TYLLIYQMKN SIEPDDVVVN GLLYALKHDN
SDIRKTCANL ISYISHEIEE IPLALFKAFV IAMLCTVKDK NSAVRCASEA CLVHLLGVRE
DGTTKFMERL VGLDGYQQQS LKNVIFRYKE RSEDESWKII DDIDYSYKLN LCKKYF
//
