ID A0A0V0ZZG1_9BILA Unreviewed; 698 AA.
AC A0A0V0ZZG1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Hypoxia-inducible factor 1 {ECO:0000313|EMBL:KRY17921.1};
GN Name=hif-1 {ECO:0000313|EMBL:KRY17921.1};
GN ORFNames=T12_132 {ECO:0000313|EMBL:KRY17921.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY17921.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY17921.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY17921.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY17921.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDQ01000054; KRY17921.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0ZZG1; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR23043; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA; 1.
DR PANTHER; PTHR23043:SF17; PROTEIN SIMILAR; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054783}.
FT DOMAIN 23..77
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 110..167
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 274..320
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
SQ SEQUENCE 698 AA; 77929 MW; 99E6F41FC33C288F CRC64;
MLPVKKRSII YNQIISKRLN VEKRREKSRH AARYRRQSEA HLFTDLYEIL PLTSEPTFYH
LDRIAVLRVA AALCRLRAVT PAILDSPNQL PALKDGCHVE QSLYDCFDNS AILIVDSTGL
IIYVSLSISF CIGITQTDLI GRSLFEYVHP DDAVDLNQAF QTCDENAEER SLILRVKSAL
SARGRSLSLK SCVYKAFSFT LKYAQSKQQQ NSVDIVNVDV ALKSLNQRKK RITGNENFYG
KYFFMFGSVV MQNCQGASFP TETIVTRHSM NMQIRYVGNG LAELLGYDAK LITGQSFFKL
VHPDDVIRFT LCVQLLYEKG YMRTGYYRML TQDGNVLWVI TEGSVVSENS RGQRAQRVLC
FHRPVGRACS SVDFSSTVAA KQYVKPPTAS ATANPNTMAN ITQSVPVFKS RSLSSEVPVR
PVVTFYDSAL PKELKKLLVS QSSMYGTAQH TADNSSSSIS YPNDWSSTFY ESISEDQTVQ
KGCMPEYQNY DNSNSVSQID SGNGSSCSNS CAGSFANEAP ELSSLTPFVN FQDLLTLQNE
GYQVNFSFNT NNSGSVEEKG SPPLNITMPS QLKRVASSRL PMKRPYPNCK LDESAFEITP
EAGNAIGDPF SPWHPCKMGD WNEQFDQDTP PDLISLETAN LLESAMTTLF QDQRGACGME
NAPRNSAANG HTFDLGLEFR FQDRMDGDVD DRGERFAQ
//
