ID A0A0V1A3I0_9BILA Unreviewed; 708 AA.
AC A0A0V1A3I0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Tetratricopeptide repeat protein 8 {ECO:0000313|EMBL:KRY19382.1};
GN Name=Ttc8 {ECO:0000313|EMBL:KRY19382.1};
GN ORFNames=T12_15692 {ECO:0000313|EMBL:KRY19382.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY19382.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY19382.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY19382.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY19382.1}.
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DR EMBL; JYDQ01000036; KRY19382.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1A3I0; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
DR GO; GO:1905515; P:non-motile cilium assembly; IEA:InterPro.
DR CDD; cd21341; TTC8_N; 1.
DR CDD; cd00199; WAP; 2.
DR Gene3D; 4.10.75.10; Elafin-like; 3.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR028796; BBS8.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR008197; WAP_dom.
DR PANTHER; PTHR44177; TETRATRICOPEPTIDE REPEAT PROTEIN 8; 1.
DR PANTHER; PTHR44177:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 8; 1.
DR Pfam; PF13181; TPR_8; 2.
DR Pfam; PF00095; WAP; 3.
DR SMART; SM00028; TPR; 5.
DR SMART; SM00217; WAP; 3.
DR SUPFAM; SSF57256; Elafin-like; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS51390; WAP; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 314..347
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 516..563
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 582..628
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 654..700
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT REGION 47..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 78735 MW; 090BD11FDF3A95B3 CRC64;
MHIQAAWLLK LNCIVCRTRI DDTEFEETGL AEELMNEEVL ANMPRPATSL RKPQSASGNG
QGSRPTTKSG RPVTGILRPG SQIGRNDTFE SVLRTGRSAN SSRPITSMTG RFVRLGTASM
IANKDGTFIN VSRLNLSKYA NQSQLARPLF EYLLFSLNDV RLAFQLASMA TEASEFKDCY
WKIQIARCYM RIGLNREAEK QLKSAYALQP SVTTGLLLSK VYCAIDQPLK AIESLRQTLT
QFPDEISLLK ALGRIYENLN DFHQSEICFK QVLKRESVDV ESIACLATHY FYNDRPELAQ
RFFRRLLQMG VMTTETLLNI GLCCFNAQQF DLAIDCLQQA ITLAEDEQAA DVWYNVGKIA
LATGDIYWAR QCYSLCLAYS SDYAEAWCDL GVLEMHENNT DQLGEYGLSL NAVKRALEIN
PEHVPSKELN KRLFNLLPKM NQTTRSTIKS VILKKGPSGK EWNCTSRNQN LKKFQPPKIT
IIIFGDLQDS VNDQSLIDVT MEKAVEILQN AHAYASANKP GICPITPRGW NSGSGRDCTT
DYDCRGPEKC CPRGHRYRCT MPTENHRPAV PPLPGEDIDP DMGVTPGECP YVPPEGGTRI
DRCLRDSECR HGKKCCMGAI GLECMTPIHG GFPPTAGGHV PAVPPPTNNI DPGMAVTPGE
CPYVPPGGGT RIDRCQRDSD CRYGKKCCMG AYGLECLRPK RRGSNFAI
//
