ID   A0A0V1CB31_TRIBR        Unreviewed;      1058 AA.
AC   A0A0V1CB31;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Anaphase-promoting complex subunit 2 {ECO:0000313|EMBL:KRY46537.1};
GN   Name=ANAPC2 {ECO:0000313|EMBL:KRY46537.1};
GN   ORFNames=T03_14656 {ECO:0000313|EMBL:KRY46537.1};
OS   Trichinella britovi (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=45882 {ECO:0000313|EMBL:KRY46537.1, ECO:0000313|Proteomes:UP000054653};
RN   [1] {ECO:0000313|EMBL:KRY46537.1, ECO:0000313|Proteomes:UP000054653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS120 {ECO:0000313|EMBL:KRY46537.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY46537.1}.
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DR   EMBL; JYDI01000283; KRY46537.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V1CB31; -.
DR   Proteomes; UP000054653; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   InterPro; IPR044554; APC2-like.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054653};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   TRANSMEM        786..814
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        871..894
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        906..931
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        989..1008
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1028..1047
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          9..34
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          416..652
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   1058 AA;  124603 MW;  444C1E36E01127C0 CRC64;
     MASEEPEFYP CNECTRAFWT EFEKEKHVLS CHTGALVWKG VRLMYPSGVQ SNCRFIFECE
     LKNRILPEFF DEIEKAIDEH VLAGKIISKN ILKYIDVFNR AVSVLYVNLK KYENGEFELD
     WRSIVEEFKK QYHSLNPVKF EQLFEVLYRV WFWIYFSDQA SKFSRREENR RTSCLVCLED
     SASCVCEEFR SKIIEANNFL IALDFRIPEL SLLCLRIAQG MVRDKIVIVV RRLEEYEFRG
     LQNIFSYLKK VVFGWLYVVM RRKVEDPFAE DLDVNTFLLR CEANLQMATF EIYGRTLISM
     VFQLIESFPS SYQIWMDLRY CMQRTGPCLD GDFINEVKKF VRLRILAQNT TTARILILYI
     KLYRALHIVF IPDSMATGIF HNIQAFLKSR CNLLSRAIAL FRRPQLMKYL GQELSFNPET
     FPDECTNELE NKFKYPVESL MDRPGIYPAT GKNFITARML IDLSGSQQDF FNEYRKILSA
     KLIRRFYRAC AFEYHILKSI DSSANSDYHY QCQMMIRDVF NSKAFETAYS EKMIRENIKL
     MPVHCIVASA NSWPEFAKES LVLPDSIGEY FAKISEYFKQ WKRSRILHLI PNLGSVHLQM
     RLNGREMQYI VEPCCACIIL QFANNIEISI AELCEKLKAP YKEIERSLNF WFQAGVLGSK
     KNANWYLRPS SNWVSQACIG RRPCEEIGIE DEFAISEEDG EDAINEYILS LEEYWPTMRG
     WFQRFESLTP DRAYLMLKIL VRQKEMLTVD IVKRYFQMKL EQVKIKTFLN QCSCEVMNDK
     KSDTEIALLC SVNFTIGILV VVINTIPFSI LLVMKKFNSE ISLVFVTIQM IDGVQFLIRG
     VRCNTISKWS YVPLVFIGEC LMTNFEIYLR LFYHLARVCT MTLITVNCIL LFLMPRVHQK
     LEKWNFFQIL ILILTILSVL YATIICLYVW MNGSGGGKIP QFCYYEQVLP RNYRRLAFVF
     NFVLYNLDHH FQKRFSDSKE KLSESKERIA IVCRLAVFIV IEASLRIYPK TFFSFMLKES
     INLTVPNILY WSSNILASIY SVIYCFINPC IKHFFKKF
//