ID A0A0V1GYW2_9BILA Unreviewed; 654 AA.
AC A0A0V1GYW2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=TWiK family of potassium channels protein 7 {ECO:0000313|EMBL:KRZ03221.1};
GN Name=twk-7 {ECO:0000313|EMBL:KRZ03221.1};
GN ORFNames=T11_1244 {ECO:0000313|EMBL:KRZ03221.1};
OS Trichinella zimbabwensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=268475 {ECO:0000313|EMBL:KRZ03221.1, ECO:0000313|Proteomes:UP000055024};
RN [1] {ECO:0000313|EMBL:KRZ03221.1, ECO:0000313|Proteomes:UP000055024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS1029 {ECO:0000313|EMBL:KRZ03221.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRZ03221.1}.
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DR EMBL; JYDP01000200; KRZ03221.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V1GYW2; -.
DR Proteomes; UP000055024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR003092; 2pore_dom_K_chnl_TASK.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR PANTHER; PTHR11003:SF333; TWIK FAMILY OF POTASSIUM CHANNELS PROTEIN 7; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR PRINTS; PR01095; TASKCHANNEL.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
DR PROSITE; PS50853; FN3; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857, ECO:0000313|EMBL:KRZ03221.1};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000055024};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 15..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 454..551
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 552..647
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 654 AA; 75591 MW; 2C59FD2CC1860283 CRC64;
MPFVENIQTS KMQRIQSIIA NALKLASGLL LLHSDRHNRL VMEERPSVDT SQHCQQQDED
DTLILDKTLQ IGSHNKTTST SQWKHYFYLI LPHASLIIVS FLYTLIGAFV FMKLEQPHIR
HLYNQKMIQM KADKDLLLER LIEMSRAKSS MDEGQTEFRN FVRSIYSMHK WNRWRNTEND
RYARIVLQPN EISLNELIHP GQEWNFAAAL FFVLTTLTTI GYGDVTPLTK EGRIFCICYC
IVGIPLFLVT TANTAKFLSS GVYYLYVRYI LIKEKLLKTS GCWWSKRVEY VHNDDRDNEK
ILLSDLKKIQ YVRLSAPAIL LIVFGYCILG AALMQQIEPW AFIDSLYFTT ISILTVGFGD
IVPTAFHSLY IPVVYILFGL VITTMAVDTV GVQYVQRIHQ FGRSMTNADY IHLLRRMKMR
KFESDEINTL PQTDMMAKIP TDSSPSSKRR SITDPLSVQV INVTPYSIKL KWDEGLEQRP
DEEYILKYRA KGTFSLADHK QKRQYSLSLS DREYEINNLR SFTVYSITIS RTYKKQEATK
RNLVVITEPE SSPQDLAIAE VNQDSILLSW KPPFKNKHLV KAYAIYCTTD VELPYEGWRK
ILVPPNVFTC TINDINDISN CFFSMCSVYD TYHSPLSKPV SVVLSNTSKI TEID
//
